The neuronal PlKfyve complex regulates neurotransmission and neurodegeneration (2010–2013)

Abstract:
Neuronal communication is essential for the functioning of our bodies and mind. We have identified a novel pathway for the regulation of this process involving a little studied lipid, Pl3, 5P2. This lipid also appears to be important for neuronal survival. We will investigate the regulation and function of this lipid in neurons. The outcomes of this proposal will be an important step closer to understanding the processes underlying neuronal communication and neurodegeneration.
Grant type:
NHMRC Project Grant
Researchers:
  • Professor and Academic Senior Group
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    Affiliate Professor of Institute fo
    Institute for Molecular Bioscience
  • Head of School
    School of Biomedical Sciences
    Faculty of Medicine
    Head of School
    Faculty of Medicine
    Professor
    Queensland Brain Institute
    Professor and Professorial Research
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    Head of School of Biomedical Scienc
    School of Biomedical Sciences
    Faculty of Medicine
Funded by:
National Health and Medical Research Council