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Confocal and single molecule microscopes for Systems Microscopy (ARC LIEF grant administered by The University of New South Wales) (2018–2019)

Abstract:
Confocal and single molecule microscopes for systems microscopy. This project aims to establish Australia¿s first system microscopy facility with dedicated live-cell confocal and single-molecule fluorescence microscopes. In systems microscopy, the imaging workflow is automated so that large and unbiased data sets of the spatiotemporal organisation of molecules and cells can be generated. Combined with statistical and bioinformatics analyses, image-derived data provides system-wide information that is not easily obtainable with other approaches. The project will enable Australian researchers to image and analyse the full complexity of biological systems, potentially transforming cell biology, drug development and understanding the molecular basis of disease. It will also demonstrate how the capacity of microscopy facilities can be enhanced and bias in imaging data reduced by automating data acquisition and mining of image-based data.
Grant type:
University of New South Wales
Researchers:

  • Professor Frederic Meunier

    Professor and Academic Senior Group
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
    Affiliate Professor of Institute fo
    Institute for Molecular Bioscience
Funded by:
University of New South Wales