How does timing affect mammalian brain development and evolution? (2020–2023)

Abstract:
This project aims to generate fundamental knowledge on the origin of diversity in mammalian brain circuits by studying development of marsupials and rodents. The expected outcome is to elucidate how differences in the timing, rate and sequence of development of gene expression, cell differentiation and circuit formation can relate to the origin of key evolutionary innovations in the mammalian brain. The significance of understanding the dynamics of developmental systems that shape complex brain traits includes establishing new developmental paradigms in evolutionary theory, generating new tools to investigate and manipulate brain gene expression in vivo, and the potential discovery of the causes of neurodevelopmental dysfunction.
Grant type:
ARC Discovery Projects
Researchers:
  • Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Associate Professor
    School of Biomedical Sciences
    Faculty of Medicine
    Affiliate Senior Research Fellow of
    Queensland Brain Institute
  • Senior Research Fellow
    School of Biomedical Sciences
    Faculty of Medicine
    Senior Research Fellow
    School of Biomedical Sciences
    Faculty of Medicine
    Affiliate Research Fellow
    Queensland Brain Institute
Funded by:
Australian Research Council