Molecular basis of glutamate receptor trafficking in neuronal plasticity (2023–2026)

Abstract:
Neurons communicate via synapses, where chemicals (such as glutamate) are released to transmit neuronal signals. This proposal is aimed at understanding the molecular mechanisms of neuronal communication and adaptive plasticity, which are essential for normal brain function. The proposed research will combine biophysical, biochemical, molecular and cell biological assays to elucidate how the trafficking of glutamate receptors is regulated in neurons during plasticity and learning. The outcomes will enhance our understanding of how neural plasticity is generated and maintained, knowledge that is critical for our understanding of the cellular correlates of information, sensory and motor processing, as well as learning, memory and cognition.
Grant type:
ARC Future Fellowships
Researchers:
  • ARC Future Fellow - Group Leader
    Queensland Brain Institute
    of Clem Jones Centre for Ageing and
    Clem Jones Centre for Ageing Dementia Research
    Queensland Brain Institute
Funded by:
Australian Research Council