Bio-inspired Nanoparticles for Mechano-Regulation of Stem Cell Fate (2024–2027)

Abstract:
Mechanical stimulation plays a critical role in regulating stem cell fate. Nanostructure-mediated mechanical cues can precisely stimulate stem cells, but predicting their impact on stem cell differentiation is challenging. This project aims to engineer nanostructures to regulate stem cell fate and gain a fundamental understanding of the mechanical properties that affect cell function. The expected outcomes and benefits of this project include a new fundamental understanding of the effect of mechanical properties on cell function, novel insights into the regulation of stem cell fate, and the development of a new class of roughness-tunable materials suitable for use in tissue engineering and pharmaceutical applications.
Grant type:
ARC Discovery Projects
Researchers:
  • NHMRC Emerging Leadership Fellow
    Australian Institute for Bioengineering and Nanotechnology
    NHMRC Emerging Leadership Fellow
    Australian Institute for Bioengineering and Nanotechnology
  • Principal Research Fellow
    Australian Institute for Bioengineering and Nanotechnology
    Principal Research Fellow
    Australian Institute for Bioengineering and Nanotechnology
Funded by:
Australian Research Council