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Protein Structure and Dynamics by Electron / Nuclear Paramagnetic Resonance (ARC Discovery Project led by The Australian National University) (2024–2027)

Abstract:
This interdisciplinary project aims to establish new magnetic resonance methods for the analysis of protein structure and motion at low concentrations and in physiological conditions that are otherwise difficult or impossible to study. It brings together four different research groups with expertise in advanced biochemistry, modern magnetic spectroscopy and high-performance computing. The project expects to develop tools to study protein structure, protein-protein association and protein-ligand interactions of established drug-targets. Expected outcomes include new techniques that quickly inform how drugs work, providing significant benefits to many researchers studying biomolecules, and supporting Australia¿s growing biotechnology sector.
Grant type:
Australian National University
Researchers:

  • Associate Professor Jeffrey Harmer

    Principal Research Fellow
    Centre for Advanced Imaging
    Australian Institute for Bioengineering and Nanotechnology
    Principal Research Fellow
    Centre for Advanced Imaging
    Australian Institute for Bioengineering and Nanotechnology
    Affiliate Associate Professor of Sc
    School of Chemistry and Molecular Biosciences
    Faculty of Science

  • Dr Rhia Stone

    Postdoctoral Research Fellow/Resear
    Institute for Molecular Bioscience
Funded by:
Australian National University