Dr Hafiz Abdul-Aziz

Research Fellow

UQ Centre for Clinical Research
Faculty of Medicine

Overview

Dr. Mohd Hafiz Abdul-Aziz is an Early Career Research Fellow and Clinical Research Pharmacist at the University of Queensland Centre for Clinical Research (UQCCR), Australia. He currently leads the Clinical Dosing Studies and Knowledge Translation Workstream within the Antimicrobial Optimisation Group and the Centre for Research Excellence for Personalising Antimicrobial Dosing to Reduce Resistance (CRE RESPOND) at UQCCR. Dr. Abdul-Aziz holds a Bachelor of Pharmacy (IIUM) and a Master of Clinical Pharmacy (UKM) from Malaysia and completed his PhD at the University of Queensland in 2016. His doctoral thesis focused on pharmacokinetic/pharmacodynamic-optimised beta-lactam dosing in critically ill patients.

As a clinical pharmacist with a strong interest in clinical research, Dr. Abdul-Aziz is particularly focused on multi-centre and multi-national collaborations. His current research program aims to develop innovative methods for optimising antimicrobial dosing and delivery to improve patient outcomes in the ICU. He has extensive experience in designing and conducting multi-national clinical pharmacokinetic studies in the ICU. Over the past five years, he has led or coordinated eight multi-national antimicrobial pharmacokinetic studies, including the ASAP ECMO, BLING 3, BLING 3 PK/PD, and PNEUDOS studies.

Dr. Abdul-Aziz is a Fellow of the International Society of Antimicrobial Chemotherapy (ISAC) and serves as the Chair of the Infections in the ICU and Sepsis Working Group of ISAC. He has maintained active collaborations with over 100 collaborators from 36 countries.

Qualifications

  • Doctor of Philosophy, The University of Queensland

Publications

  • Abdul-Aziz, Mohd H., Hammond, Naomi E., Brett, Stephen J., Cotta, Menino O., De Waele, Jan J., Devaux, Anthony, Di Tanna, Gian Luca, Dulhunty, Joel M., Elkady, Hatem, Eriksson, Lars, Hasan, M Shahnaz, Khan, Ayesha Bibi, Lipman, Jeffrey, Liu, Xiaoqiu, Monti, Giacomo, Myburgh, John, Novy, Emmanuel, Omar, Shahed, Rajbhandari, Dorrilyn, Roger, Claire, Sjövall, Fredrik, Zaghi, Irene, Zangrillo, Alberto, Delaney, Anthony and Roberts, Jason A. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis. JAMA. doi: 10.1001/jama.2024.9803

  • Shekar, Kiran, Abdul-Aziz, Mohd H, Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M, Kim, Hyung-Sook, Levkovich, Bianca J, Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C, Welch, Susan A, Zacharias, David, Fraser, John F. and Roberts, Jason A (2023). Antimicrobial exposures in critically ill patients receiving extracorporeal membrane oxygenation. American Journal of Respiratory and Critical Care Medicine, 207 (6), 704-720. doi: 10.1164/rccm.202207-1393oc

  • Roberts, Jason A., Bellomo, Rinaldo, Cotta, Menino O., Koch, Birgit C. P., Lyster, Haifa, Ostermann, Marlies, Roger, Claire, Shekar, Kiran, Watt, Kevin and Abdul-Aziz, Mohd H. (2022). Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software. Intensive Care Medicine, 48 (10), 1338-1351. doi: 10.1007/s00134-022-06847-2

  • Abdul-Aziz, Mohd H., Alffenaar, Jan-Willem C., Bassetti, Matteo, Bracht, Hendrik, Dimopoulos, George, Marriott, Deborah, Neely, Michael N., Paiva, Jose-Artur, Pea, Federico, Sjovall, Fredrik, Timsit, Jean F., Udy, Andrew A., Wicha, Sebastian G., Zeitlinger, Markus, De Waele, Jan J., Roberts, Jason A., the Infection Section of European Society of Intensive Care Medicine (ESICM), Pharmacokinetic/pharmacodynamic and Critically Ill Patient Study Groups of European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Group of International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) and Infections in the ICU and Sepsis Working Group of International Society of Antimicrobial Chemotherapy (ISAC) (2020). Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#. Intensive Care Medicine, 46 (6), 1127-1153. doi: 10.1007/s00134-020-06050-1

  • Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016). Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 42 (10), 1535-1545. doi: 10.1007/s00134-015-4188-0

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Supervision

View all Supervision

Publications

Featured Publications

  • Abdul-Aziz, Mohd H., Hammond, Naomi E., Brett, Stephen J., Cotta, Menino O., De Waele, Jan J., Devaux, Anthony, Di Tanna, Gian Luca, Dulhunty, Joel M., Elkady, Hatem, Eriksson, Lars, Hasan, M Shahnaz, Khan, Ayesha Bibi, Lipman, Jeffrey, Liu, Xiaoqiu, Monti, Giacomo, Myburgh, John, Novy, Emmanuel, Omar, Shahed, Rajbhandari, Dorrilyn, Roger, Claire, Sjövall, Fredrik, Zaghi, Irene, Zangrillo, Alberto, Delaney, Anthony and Roberts, Jason A. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis. JAMA. doi: 10.1001/jama.2024.9803

  • Shekar, Kiran, Abdul-Aziz, Mohd H, Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Cho, Young-Jae, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Jakob, Stephan M, Kim, Hyung-Sook, Levkovich, Bianca J, Lim, Sung Yoon, McGuinness, Shay, Parke, Rachael, Pellegrino, Vincent, Que, Yok-Ai, Reynolds, Claire, Rudham, Sam, Wallis, Steven C, Welch, Susan A, Zacharias, David, Fraser, John F. and Roberts, Jason A (2023). Antimicrobial exposures in critically ill patients receiving extracorporeal membrane oxygenation. American Journal of Respiratory and Critical Care Medicine, 207 (6), 704-720. doi: 10.1164/rccm.202207-1393oc

  • Roberts, Jason A., Bellomo, Rinaldo, Cotta, Menino O., Koch, Birgit C. P., Lyster, Haifa, Ostermann, Marlies, Roger, Claire, Shekar, Kiran, Watt, Kevin and Abdul-Aziz, Mohd H. (2022). Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software. Intensive Care Medicine, 48 (10), 1338-1351. doi: 10.1007/s00134-022-06847-2

  • Abdul-Aziz, Mohd H., Alffenaar, Jan-Willem C., Bassetti, Matteo, Bracht, Hendrik, Dimopoulos, George, Marriott, Deborah, Neely, Michael N., Paiva, Jose-Artur, Pea, Federico, Sjovall, Fredrik, Timsit, Jean F., Udy, Andrew A., Wicha, Sebastian G., Zeitlinger, Markus, De Waele, Jan J., Roberts, Jason A., the Infection Section of European Society of Intensive Care Medicine (ESICM), Pharmacokinetic/pharmacodynamic and Critically Ill Patient Study Groups of European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Group of International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) and Infections in the ICU and Sepsis Working Group of International Society of Antimicrobial Chemotherapy (ISAC) (2020). Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#. Intensive Care Medicine, 46 (6), 1127-1153. doi: 10.1007/s00134-020-06050-1

  • Abdul-Aziz, Mohd H., Sulaiman, Helmi, Mat-Nor, Mohd-Basri, Rai, Vineya, Wong, Kang K., Hasan, Mohd S., Abd Rahman, Azrin N., Jamal, Janattul A., Wallis, Steven C., Lipman, Jeffrey, Staatz, Christine E. and Roberts, Jason A. (2016). Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis. Intensive Care Medicine, 42 (10), 1535-1545. doi: 10.1007/s00134-015-4188-0

Book Chapter

  • Kirk, Christa Jefferis, Abdul-Aziz, Mohd H., Roberts, Jason A., Valencia, Eleonore, Watt, Kevin, MacLaren, Graeme and Shekar, Kiran (2022). Pharmacology. Extracorporeal life support: The ELSO red book. (pp. 643-654) edited by Graeme Maclaren, Daniel Brodie, Roberto Lorusso, Giles Peek, Ravi Thiagarajan and Leen Vercaemst. Ann Arbor, MI, United States: Extracorporeal Life Support Organization.

  • Cheng, Vesa, Abdul-Aziz, Mohd H. and Shekar, Kiran (2022). Challenges of antimicrobial therapy in ECMO patients. Extracorporeal membrane oxygenation: an interdisciplinary problem-based learning approach. (pp. 191-200) edited by Marc O. Maybauer. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/med/9780197521304.003.0018

  • Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Levkovich, Bianca and Roberts, Jason A. (2019). Clinical Pharmacy Considerations in ICU. Encyclopedia of Pharmacy Practice and Clinical Pharmacy. (pp. 849-865) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-812735-3.00576-8

  • Jamal, Janattul-Ain, Abdul-Aziz, Mohd-Hafiz, Levkovich, Bianca and Roberts, Jason A. (2019). Clinical pharmacy considerations in ICU. Encyclopedia of pharmacy practice and clinical pharmacy. (pp. 849-865) edited by Zaheer-Ud-Din Babar. Oxford, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-812735-3.00576-8

  • Abdul-Aziz, M. H., Shekar, Kiran and Roberts, Jason A. (2018). Antibiotic dosing during extracorporeal membrane oxygenation. Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill. (pp. 151-171) edited by Andrew A. Udy, Jason A. Roberts and Jeffrey Lipman. Gateway East, Singapore: Springer . doi: 10.1007/978-981-10-5336-8_8

Journal Article

Conference Publication

Other Outputs

PhD and MPhil Supervision

Current Supervision

  • Master Philosophy — Associate Advisor

    Other advisors: