The University of Queensland

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, Dinesh, Clayton, Zoe E., Prowse, Andrew, Dingwall, Steve, Kim, Sul Ki, Reyes, Leila, George, Jacob, Shah, Haisam, Chen, Siqi, Leung, Halina H. L., Hume, Robert D., Tjahjadi, Laurentius, Igoor, Sindhu, Skelton, Rhys J. P., Hing, Alfred, Paterson, Hugh, Foster, Sheryl L., Pearson, Lachlan, Wilkie, Emma, Marcus, Alan D., Jeyaprakash, Prajith, Wu, Zhixuan, Chiu, Han Shen, Ongtengco, Cherica Felize J., Mulay, Onkar, McArthur, Jeffrey R., Barry, Tony, Lu, Juntang, Tran, Vu ... Chong, James J. H. (2024). Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. Nature Cardiovascular Research, 3 (2), 145-165. doi: 10.1038/s44161-023-00419-3

Functional arrays of human pluripotent stem cell-derived cardiac microtissues

Thavandiran, Nimalan, Hale, Christopher, Blit, Patrick, Sandberg, Mark L., McElvain, Michele E., Gagliardi, Mark, Sun, Bo, Witty, Alec, Graham, George, Do, Van T. H., Bakooshli, Mohsen Afshar, Le, Hon, Ostblom, Joel, McEwen, Samuel, Chau, Erik, Prowse, Andrew, Fernandes, Ian, Norman, Andreea, Gilbert, Penney M., Keller, Gordon, Tagari, Philip, Xu, Han, Radisic, Milica and Zandstra, Peter W. (2020). Functional arrays of human pluripotent stem cell-derived cardiac microtissues. Scientific Reports, 10 (1) 6919. doi: 10.1038/s41598-020-62955-3

Generation of fibroblast-derived induced pluripotent stem cell (iPSC) lines from two paediatric patients with phenylketonuria

Veleva, Desi, Ay, Merve, Ovchinnikov, Dmitry A., Prowse, Andrew B. J., Menezes, Minal J. and Nafisinia, Michael (2024). Generation of fibroblast-derived induced pluripotent stem cell (iPSC) lines from two paediatric patients with phenylketonuria. Stem Cell Research, 77 103405, 1-7. doi: 10.1016/j.scr.2024.103405

Generation of two lymphoblastoid-derived induced pluripotent stem cell (iPSC) lines from patients with phenylketonuria

Veleva, Desi, Ay, Merve, Ovchinnikov, Dmitry A., Prowse, Andrew B.J., Menezes, Minal J. and Nafisinia, Michael (2024). Generation of two lymphoblastoid-derived induced pluripotent stem cell (iPSC) lines from patients with phenylketonuria. Stem Cell Research, 77 103407, 103407. doi: 10.1016/j.scr.2024.103407

Production of induced pluripotent stem cell derived cardiomyocytes in a scalable vertical wheel bioreactor system

Dingwall, S., Ongtenco, C., Sun, J., Power, D., Gray, P. and Prowse, A. (2024). Production of induced pluripotent stem cell derived cardiomyocytes in a scalable vertical wheel bioreactor system. Cytotherapy, 26 (6), S223-S224. doi: 10.1016/j.jcyt.2024.03.453

Analysis of three characterization assays reveals ddPCR of LIN28A as the most sensitive for the detection of residual pluripotent stem cells in cellular therapy products

Sun, Jinda, Yates, Clarissa, Dingwall, Steve, Ongtengco, Cherica, Power, Dominique, Gray, Peter and Prowse, Andrew (2024). Analysis of three characterization assays reveals ddPCR of LIN28A as the most sensitive for the detection of residual pluripotent stem cells in cellular therapy products. Cytotherapy. doi: 10.1016/j.jcyt.2024.05.019

Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, Dinesh, Clayton, Zoe E., Prowse, Andrew, Dingwall, Steve, Kim, Sul Ki, Reyes, Leila, George, Jacob, Shah, Haisam, Chen, Siqi, Leung, Halina H. L., Hume, Robert D., Tjahjadi, Laurentius, Igoor, Sindhu, Skelton, Rhys J. P., Hing, Alfred, Paterson, Hugh, Foster, Sheryl L., Pearson, Lachlan, Wilkie, Emma, Marcus, Alan D., Jeyaprakash, Prajith, Wu, Zhixuan, Chiu, Han Shen, Ongtengco, Cherica Felize J., Mulay, Onkar, McArthur, Jeffrey R., Barry, Tony, Lu, Juntang, Tran, Vu ... Chong, James J. H. (2024). Cellular heterogeneity of pluripotent stem cell-derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. Nature Cardiovascular Research, 3 (2), 145-165. doi: 10.1038/s44161-023-00419-3

Functional arrays of human pluripotent stem cell-derived cardiac microtissues

Thavandiran, Nimalan, Hale, Christopher, Blit, Patrick, Sandberg, Mark L., McElvain, Michele E., Gagliardi, Mark, Sun, Bo, Witty, Alec, Graham, George, Do, Van T. H., Bakooshli, Mohsen Afshar, Le, Hon, Ostblom, Joel, McEwen, Samuel, Chau, Erik, Prowse, Andrew, Fernandes, Ian, Norman, Andreea, Gilbert, Penney M., Keller, Gordon, Tagari, Philip, Xu, Han, Radisic, Milica and Zandstra, Peter W. (2020). Functional arrays of human pluripotent stem cell-derived cardiac microtissues. Scientific Reports, 10 (1) 6919. doi: 10.1038/s41598-020-62955-3

Methods for expansion of 3D cultures of human embryonic stem cells using a thermoresponsive polymer

Chen, Xiaoli, Harkness, Linda, Jia, Zhongfan, Prowse, Andrew, Monteiro, Michael J. and Gray, Peter P. (2018). Methods for expansion of 3D cultures of human embryonic stem cells using a thermoresponsive polymer. Tissue Engineering. Part C. Methods, 24 (3), 146-157. doi: 10.1089/ten.TEC.2017.0331

Transforming the promise of pluripotent stem cell-derived cardiomyocytes to a therapy: challenges and solutions for clinical trials

Prowse, Andrew B. J., Timmins, Nicholas E., Yau, Terrence M., Li, Ren-Ke, Weisel, Richard D., Keller, Gordon and Zandstra, Peter W. (2014). Transforming the promise of pluripotent stem cell-derived cardiomyocytes to a therapy: challenges and solutions for clinical trials. Canadian Journal of Cardiology, 30 (11), 1335-1349. doi: 10.1016/j.cjca.2014.08.005

Thermoresponsive worms for expansion and release of human embryonic stem cells

Chen, Xiaoli, Prowse, Andrew B. J., Jia, Zhongfan, Tellier, Helena, Munro,Trent P., Gray, Peter P. and Monteiro, Michael J. (2014). Thermoresponsive worms for expansion and release of human embryonic stem cells. Biomacromolecules, 15 (3), 844-855. doi: 10.1021/bm401702h

Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro

Prowse, Andrew B. J., Chong, Fenny, Elliott, David A., Elefanty, Andrew G., Stanley, Edouard G., Gray, Peter P., Munro, Trent P. and Osborne, Geoffrey W. (2012). Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro. PLoS One, 7 (12) e52214, e52214-1-e52214-10. doi: 10.1371/journal.pone.0052214

Stem cell integrins: Implications for ex-vivo culture and cellular therapies

Prowse, Andrew B. J., Chong, Fenny, Gray, Peter P. and Munro, Trent P. (2011). Stem cell integrins: Implications for ex-vivo culture and cellular therapies. Stem Cell Research, 6 (1), 1-12. doi: 10.1016/j.scr.2010.09.005

Long term culture of human embryonic stem cells on recombinant vitronectin in ascorbate free media

Prowse, Andrew B. J., Doran, Michael R., Cooper-White, Justin J., Chong, Fenny, Munro, Trent P., Fitzpatrick, Jane, Chung, Tung-Liang, Haylock, David N., Gray, Peter P. and Wolvetang, Ernst J. (2010). Long term culture of human embryonic stem cells on recombinant vitronectin in ascorbate free media. Biomaterials, 31 (32), 8281-8288. doi: 10.1016/j.biomaterials.2010.07.037

Defined high protein content surfaces for stem cell culture

Doran, Michael R., Frith, Jessica E., Prowse, Andrew B. J., Fitzpatrick, Jane, Wolvetang, Ernst J., Munro, Trent P., Gray, Peter P. and Cooper-White, Justin J. (2010). Defined high protein content surfaces for stem cell culture. Biomaterials, 31 (19), 5137-5142. doi: 10.1016/j.biomaterials.2010.03.015

Multiplexed Staining of Live Human Embryonic Stem Cells for Flow Cytometric Analysis of Pluripotency Markers

Prowse, ABJ, Wilson, J, Osborne, GW, Gray, PP and Wolvetang, EJ (2009). Multiplexed Staining of Live Human Embryonic Stem Cells for Flow Cytometric Analysis of Pluripotency Markers. Stem Cells and Development, 18 (8), 1135-1139. doi: 10.1089/scd.2009.0080

A rapid, cost-effective method for counting human embryonic stem cell numbers as clumps

Prowse, ABJ, Wolvetang, EJ and Gray, PP (2009). A rapid, cost-effective method for counting human embryonic stem cell numbers as clumps. Biotechniques, 47 (1), 599-606. doi: 10.2144/000113151

Identification of potential pluripotency determinants for human embryonic stem cells following proteomic analysis of human and mouse fibroblast conditioned media

Prowse, A. B. J., McQuade, L. R., Bryant, K. J., Marcal, H. and Gray, P. P. (2007). Identification of potential pluripotency determinants for human embryonic stem cells following proteomic analysis of human and mouse fibroblast conditioned media. Journal of Proteome Research, 6 (9), 3796-3807. doi: 10.1021/pr0702262

Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias

Selvakumar, D., Clayton, Z., Prowse, A., Dingwall, S., George, J., Shah, H., Paterson, H., Jeyaprakesh, P., Wu, Z., Campbell, T., Kotake, Y., Turnbull, S., Nguyen, Q., Grieve, S., Palpant, N., Pathan, F., Kizana, E., Kumar, S., Gray, P. and Chong, J. (2022). Cellular heterogeneity of pluripotent stem cell derived cardiomyocyte grafts is mechanistically linked to treatable arrhythmias. 70th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Gold Coast, QLD Australia, 11-14 August 2022. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2022.06.004

A proteome analysis of conditioned media from human neonatal fibroblasts used in the maintenance of human embryonic stem cells

Prowse, Andrew B. J., McQuade, Leon R., Bryant, Katherin J., Van Dyk, Derek D., Tuch, BBernard E. and Gray, Peter P. (2005). A proteome analysis of conditioned media from human neonatal fibroblasts used in the maintenance of human embryonic stem cells. 3rd International Proteomics Conference/1st Taiwan Proteomics Conference/2nd AOHUPO Congress, Taipei, Taiwan, 14-17 May 2004. Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/pmic.200401087

Release Media

Gray, Peter, Monteiro, Michael John, Munro, Trent Phillip and Prowse, Andrew Benjamin James (2013). Release Media. US9587104.