The University of Queensland

In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer

Bock, Nathalie, Kryza, Thomas, Shokoohmand, Ali, Röhl, Joan, Ravichandran, Akhilandeshwari, Wille, Marie-Luise, Nelson, Colleen C., Hutmacher, Dietmar W. and Clements, Judith A. (2021). In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer. Science Advances, 7 (27) eabg2564, 1-16. doi: 10.1126/sciadv.abg2564

Pearl sac gene expression profiles associated with pearl attributes in the silver-lip pearl oyster, Pinctada maxima

McDougall, Carmel, Aguilera, Felipe, Shokoohmand, Ali, Moase, Patrick and Degnan, Bernard M. (2021). Pearl sac gene expression profiles associated with pearl attributes in the silver-lip pearl oyster, Pinctada maxima. Frontiers in Genetics, 11 597459, 1-13. doi: 10.3389/fgene.2020.597459

Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo

Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas and McGovern, Jacqui A. (2020). Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo. Bone Research, 8 (1) 17, 17. doi: 10.1038/s41413-020-0092-5

Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts

Shokoohmand, Ali, Ren, Jiongyu, Baldwin, Jeremy, Atack, Anthony, Shafiee, Abbas, Theodoropoulos, Christina, Wille, Marie-Luise, Tran, Phong A., Bray, Laura J., Smith, Deborah, Chetty, Naven, Pollock, Pamela M., Hutmacher, Dietmar W., Clements, Judith A., Williams, Elizabeth D. and Bock, Nathalie (2019). Microenvironment engineering of osteoblastic bone metastases reveals osteomimicry of patient-derived prostate cancer xenografts. Biomaterials, 220 119402, 1-17. doi: 10.1016/j.biomaterials.2019.119402

Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo

Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas and McGovern, Jacqui A. (2019). Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo. Bone Research, 7 (1) 31, 1-11. doi: 10.1038/s41413-019-0072-9

Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment

Bock, Nathalie, Shokoohmand, Ali, Kryza, Thomas, Rohl, Joan, Meijer, Jonelle, Tran, Phong A., Nelson, Colleen C., Clements, Judith A. and Hutmacher, Dietmar W. (2019). Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment. Bone Research, 7 (1) 13, 1-14. doi: 10.1038/s41413-019-0049-8

A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns

Loessner, Daniela, Rockstroh, Anja, Shokoohmand, Ali, Holzapfel, Boris M., Wagner, Ferdinand, Baldwin, Jeremy, Boxberg, Melanie, Schmalfeldt, Barbara, Lengyel, Ernst, Clements, Judith A. and Hutmacher, Dietmar W. (2019). A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns. Biomaterials, 190-191, 63-75. doi: 10.1016/j.biomaterials.2018.10.014

Insulin enhances migration and invasion in prostate cancer cells by up-regulation of FOXC2

Sarkar, Phoebe L., Lee, Wendy, Williams, Elizabeth D., Lubik, Amy A., Stylianou, Nataly, Shokoohmand, Ali, Lehman, Melanie L., Hollier, Brett G., Gunter, Jennifer H. and Nelson, Colleen C. (2019). Insulin enhances migration and invasion in prostate cancer cells by up-regulation of FOXC2. Frontiers in Endocrinology, 10 481, 1-16. doi: 10.3389/fendo.2019.00481

Targeting insulin-like growth factor-I and extracellular matrix interactions in melanoma progression

Murekatete, Berline, Shokoohmand, Ali, McGovern, Jacqui, Mohanty, Lipsa, Meinert, Christoph, Hollier, Brett G., Zippelius, Alfred, Upton, Zee and Kashyap, Abhishek S. (2018). Targeting insulin-like growth factor-I and extracellular matrix interactions in melanoma progression. Scientific Reports, 8 (1) 583, 1-12. doi: 10.1038/s41598-017-19073-4

Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma

Wagner, Ferdinand, Holzapfel, Boris M., McGovern, Jacqui A., Shafiee, Abbas, Baldwin, Jeremy G., Martine, Laure C., Lahr, Christoph A., Wunner, Felix M., Friis, Thor, Bas, Onur, Boxberg, Melanie, Prodinger, Peter M., Shokoohmand, Ali, Moi, Davide, Mazzieri, Roberta, Loessner, Daniela and Hutmacher, Dietmar W. (2018). Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma. Biomaterials, 171, 230-246. doi: 10.1016/j.biomaterials.2018.04.030

A novel 3D cultured model for studying early changes in age-related macular degeneration

Shokoohmand, Ali, Jeon, June E., Theodoropoulos, Christina, Baldwin, Jeremy G., Hutmacher, Dietmar W. and Feigl, Beatrix (2017). A novel 3D cultured model for studying early changes in age-related macular degeneration. Macromolecular Bioscience, 17 (12) ARTN 1700221, 1-8. doi: 10.1002/mabi.201700221

Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load

Holzapfel, Nina Pauline, Shokoohmand, Ali, Wagner, Ferdinand, Landgraf, Marietta, Champ, Simon, Holzapfel, Boris Michael, Clements, Judith Ann, Hutmacher, Dietmar Werner and Loessner, Daniela (2017). Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load. American Journal of Cancer Research, 7 (6), 1322-1336.

The distribution of the apparent diffusion coefficient as an indicator of the response to chemotherapeutics in ovarian tumour xenografts

Tourell, Monique C., Shokoohmand, Ali, Landgraf, Marietta, Holzapfel, Nina P., Poh, Patrina S. P., Loessner, Daniela and Momot, Konstantin I. (2017). The distribution of the apparent diffusion coefficient as an indicator of the response to chemotherapeutics in ovarian tumour xenografts. Scientific Reports, 7 (1) 42905, 1-13. doi: 10.1038/srep42905

Endosteal-like extracellular matrix expression on melt electrospun written scaffolds

Muerza-Cascante, Maria Lourdes, Shokoohmand, Ali, Khosrotehrani, Kiarash, Haylock, David, Dalton, Paul D., Hutmacher, Dietmar W. and Loessner, Daniela (2016). Endosteal-like extracellular matrix expression on melt electrospun written scaffolds. Acta Biomaterialia, 52, 145-158. doi: 10.1016/j.actbio.2016.12.040

Antagonists of IGF:Vitronectin interactions inhibit IGF-I-Induced breast cancer cell functions

Kashyap, Abhishek S., Shooter, Gary K., Shokoohmand, Ali, McGovern, Jacqui, Sivaramakrishnan, Manaswini, Croll, Tristan I., Cane, Gaëlle, Leavesley, David I., Söderberg, Ola, Upton, Zee and Hollier, Brett G. (2016). Antagonists of IGF:Vitronectin interactions inhibit IGF-I-Induced breast cancer cell functions. Molecular Cancer Therapeutics, 15 (7), 1602-1613. doi: 10.1158/1535-7163.MCT-15-0907

Poly(2-oxazoline) hydrogels as next generation three-dimensional cell supports

Dargaville, Tim R., Hollier, Brett G., Shokoohmand, Ali and Hoogenboom, Richard (2014). Poly(2-oxazoline) hydrogels as next generation three-dimensional cell supports. Cell Adhesion and Migration, 8 (2), 88-93. doi: 10.4161/cam.28205

Vitronectin-master controller or micromanager?

Leavesley, David I., Kashyap, Abhishek S., Croll, Tristan, Sivaramakrishnan, Manaswini, Shokoohmand, Ali, Hollier, Brett G. and Upton, Zee (2013). Vitronectin-master controller or micromanager?. IUBMB Life, 65 (10), 807-818. doi: 10.1002/iub.1203

Preserving clinical efficacy of mesenchymal stem cells with glycosaminoglycan additives

Shokoohmand, A., Srinivasan, A., Ling, L., Silva, F. Rodrigues de Oliveira, Eio, M.Y., Lu, X., Loberas, M., Tao, K., Tan, C., Nurcombe, V., Hui, J., Smith, R. and Cool, S. (2024). Preserving clinical efficacy of mesenchymal stem cells with glycosaminoglycan additives. 30th Annual ISCT Meeting, Vancouver, BC, Canada, 29 May - 1 June 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jcyt.2024.03.116

Development and validation of a modular 3D microenvironment platform technology for studying prostate cancer- induced bone metastasis

Shokoohmand, Ali, Bock, Nathalie, Baldwin, Jeremy, Kryza, Thomas, Nelson, Colleen C., Clements, Judith A. and Hutmacher, Dietmar W. (2016). Development and validation of a modular 3D microenvironment platform technology for studying prostate cancer- induced bone metastasis. 17th Asia-Pacific Prostate Cancer Conference, Melbourne, Australia, 31 August-3 September 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Modulation of protease expression in prostate cancer cells after androgen deprivation

Kryza, Thomas, Bock, Nathalie, Shokoohmand, Ali, Tevz, Gregor, McPherson, Stephen, Lehman, Melanie, Stephens, Carson, Hollier, Brett G., Nelson, Colleen C., Williams, Elizabeth D., Hutmacher, Dietmar and Clements, Judith (2016). Modulation of protease expression in prostate cancer cells after androgen deprivation. 17th Asia-Pacific Prostate Cancer Conference, Melbourne, Australia, 31 August-3 September 2016. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

A bioengineered 3D approach to mimic the tumor-stroma microenvironment of ovarian cancer

Shokoohmand, Ali, Loessner, Daniela, Holzapfel, Boris, Wagner, Ferdinand, Baldwin, Jeremy, Rockstroh, Anja, Magdolen, Viktor, Clements, Judith and Hutmacher, Dietmar (2016). A bioengineered 3D approach to mimic the tumor-stroma microenvironment of ovarian cancer. 10th World Biomaterials Congress, Montréal, Canada, 17 May-22 May, 2016. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.fbioe.2016.01.02987

An advanced bioengineered 3D model mimicking prostate cancer-induced bone metastasis microenvironment

Shokoohmand, Ali, Bock, Nathalie, Clements, Judith and Hutmacher, Dietmar (2016). An advanced bioengineered 3D model mimicking prostate cancer-induced bone metastasis microenvironment. 10th World Biomaterials Congress, Montréal, Canada, 17 May-22 May, 2016. Lausanne, Switzerland: Frontiers Research Foundation. doi: 10.3389/conf.fbioe.2016.01.03011