Dr James Wood's research focuses primarily on the design and synthesis of organic ligands to complex inorganic radioisotopes for radiopharmaceutical applications. His work spans across the design and synthesis of these ligands, through to radiolabelling of these compounds and assessing them within animal models. He is particularly interested in applications of these ligands that grant greater flexability or utility to diagnostic and therapeutic platforms.
James works within the ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals at the Centre for Advanced Imaging, working with industry partners to excelerate the production of novel radiopharmaceuticals.
Journal Article: A first-in-class dual-chelator theranostic agent designed for use with imaging-therapy radiometal pairs of different elements
Wood, James Liam, Ghosh, Saikat, Houston, Zachary, Fletcher, Nicholas, Humphries, James, Mardon, Karine, Akhter, Dewan T., Tieu, William, Ivashkevich, Alesia, Wheatcroft, Michael P., Thurecht, Kristofer J. and Codd, Rachel (2024). A first-in-class dual-chelator theranostic agent designed for use with imaging-therapy radiometal pairs of different elements. Chemical Science. doi: 10.1039/d4sc02851a
Journal Article: Reduction-cleavable desferrioxamine B pulldown system enriches Ni(II)-superoxide dismutase from a Streptomyces proteome
Ni, Jenny, Wood, James L., White, Melanie, Lihi, Norbert, Markham, Todd E., Wang, Joseph, Chivers, Peter and Codd, Rachel (2023). Reduction-cleavable desferrioxamine B pulldown system enriches Ni(II)-superoxide dismutase from a Streptomyces proteome. RSC Chemical Biology, 4 (12), 1064-1072. doi: 10.1039/d3cb00097d
Wood, James Liam, Ghosh, Saikat, Houston, Zachary, Fletcher, Nicholas, Humphries, James, Mardon, Karine, Akhter, Dewan T., Tieu, William, Ivashkevich, Alesia, Wheatcroft, Michael P., Thurecht, Kristofer J. and Codd, Rachel (2024). A first-in-class dual-chelator theranostic agent designed for use with imaging-therapy radiometal pairs of different elements. Chemical Science. doi: 10.1039/d4sc02851a
Ni, Jenny, Wood, James L., White, Melanie, Lihi, Norbert, Markham, Todd E., Wang, Joseph, Chivers, Peter and Codd, Rachel (2023). Reduction-cleavable desferrioxamine B pulldown system enriches Ni(II)-superoxide dismutase from a Streptomyces proteome. RSC Chemical Biology, 4 (12), 1064-1072. doi: 10.1039/d3cb00097d