The University of Queensland

Morphogenesis and maturation of the hippocampal network

Dehorter, Nathalie and Ben Ari, Yehezkel (2024). Morphogenesis and maturation of the hippocampal network. Cellular and molecular neurophysiology. (pp. 491-514) edited by Constance Hammond. London, United Kingdom: Academic Press. doi: 10.1016/b978-0-323-98811-7.00013-8

Neurons

Dehorter, Nathalie and Hammond, Constance (2024). Neurons. Cellular and Molecular Neurophysiology. (pp. 3-30) Elsevier. doi: 10.1016/b978-0-323-98811-7.00001-1

Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications

Acera Mateos, P., J Sethi, A., Ravindran, A., Srivastava, A., Woodward, K., Mahmud, S., Kanchi, M., Guarnacci, M., Xu, J., W S Yuen, Z., Zhou, Y., Sneddon, A., Hamilton, W., Gao, J., M Starrs, L., Hayashi, R., Wickramasinghe, V., Zarnack, K., Preiss, T., Burgio, G., Dehorter, N., E Shirokikh, N. and Eyras, E. (2024). Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications. Nature Communications, 15 (1) 3899, 1-17. doi: 10.1038/s41467-024-47953-7

Parvalbumin Interneuron Activity in Autism Underlies Susceptibility to PTSD-like Memory Formation

Al Abed, Alice Shaam, Allen, Tiarne Vickie, Ahmed, Noorya Yasmin, Sellami, Azza, Sontani, Yovina, Rawlinson, Elise Caitlin, Marighetto, Aline, Desmedt, Aline and Dehorter, Nathalie (2024). Parvalbumin Interneuron Activity in Autism Underlies Susceptibility to PTSD-like Memory Formation. iScience, 27 (5) 109747, 109747. doi: 10.1016/j.isci.2024.109747

Neuronal Replenishment via Hydrogel-Rationed Delivery of Reprogramming Factors

Mahmoudi, Negar, Wang, Yi, Moriarty, Niamh, Ahmed, Noorya Y., Dehorter, Nathalie, Lisowski, Leszek, Harvey, Alan R., Parish, Clare L., Williams, Richard J. and Nisbet, David R. (2024). Neuronal Replenishment via Hydrogel-Rationed Delivery of Reprogramming Factors. ACS Nano, 18 (4), 3597-3613. doi: 10.1021/acsnano.3c11337

Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder

Ahmed, Noorya Yasmin, Knowles, Rhys, Liu, Lixinyu, Yan, Yiming, Li, Xiaohan, Schumann, Ulrike, Wang, Yumeng, Sontani, Yovina, Reynolds, Nathan, Natoli, Riccardo, Wen, Jiayu, Del Pino, Isabel, Mi, Da and Dehorter, Nathalie (2023). Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder. Frontiers in Cell and Developmental Biology, 11 1112062, 1-16. doi: 10.3389/fcell.2023.1112062

Developmental disruption of Erbb4 in Pet1+ neurons impairs serotonergic sub-system connectivity and memory formation

Barettino, Candela, Ballesteros-Gonzalez, Álvaro, Aylón, Andrés, Soler-Sanchis, Xavier, Ortí, Leticia, Díaz, Selene, Reillo, Isabel, García-García, Francisco, Iborra, Francisco José, Lai, Cary, Dehorter, Nathalie, Leinekugel, Xavier, Flames, Nuria and Del Pino, Isabel (2021). Developmental disruption of Erbb4 in Pet1+ neurons impairs serotonergic sub-system connectivity and memory formation. Frontiers in Cell and Developmental Biology, 9 770458, 1-17. doi: 10.3389/fcell.2021.770458

From progenitors to progeny: shaping striatal circuit development and function

Knowles, Rhys, Dehorter, Nathalie and Ellender, Tommas (2021). From progenitors to progeny: shaping striatal circuit development and function. The Journal of Neuroscience, 41 (46), 9483-9502. doi: 10.1523/JNEUROSCI.0620-21.2021

A second wave for the Neurokinin Tac2 pathway in brain research

Al Abed, A. Shaam, Reynolds, Nathan J. and Dehorter, Nathalie (2021). A second wave for the Neurokinin Tac2 pathway in brain research. Biological Psychiatry, 90 (3), 156-164. doi: 10.1016/j.biopsych.2021.02.016

Er81 transcription factor fine-tunes striatal cholinergic interneuron activity and drives habit formation

Ahmed, Noorya Yasmin, Ranjbar-Slamloo, Yadollah, Al Abed, Alice Shaam, Gao, Lingxiao, Sontani, Yovina, RCom-H'cheo-Gauthier, Alexandre, Arabzadeh, Ehsan and Dehorter, Nathalie (2021). Er81 transcription factor fine-tunes striatal cholinergic interneuron activity and drives habit formation. The Journal of Neuroscience, 41 (20), 4392-4409. doi: 10.1523/JNEUROSCI.0967-20.2021

Shifting developmental trajectories during critical periods of brain formation

Dehorter, Nathalie and Del Pino, Isabel (2020). Shifting developmental trajectories during critical periods of brain formation. Frontiers in Cellular Neuroscience, 14 283, 1-14. doi: 10.3389/fncel.2020.00283

New insights into cholinergic neuron diversity

Ahmed, Noorya Yasmin, Knowles, Rhys and Dehorter, Nathalie (2019). New insights into cholinergic neuron diversity. Frontiers in Molecular Neuroscience, 12 204, 1-12. doi: 10.3389/fnmol.2019.00204

Loss of Cntnap2 causes axonal excitability deficits, developmental delay in cortical myelination, and abnormal stereotyped motor behavior

Scott, Ricardo, Sánchez-Aguilera, Alberto, Van Elst, Kim, Lim, Lynette, Dehorter, Nathalie, Bae, Sung Eun, Bartolini, Giorgia, Peles, Elior, Kas, Martien J H, Bruining, Hilgo and Marín, Oscar (2019). Loss of Cntnap2 causes axonal excitability deficits, developmental delay in cortical myelination, and abnormal stereotyped motor behavior. Cerebral Cortex, 29 (2), 586-597. doi: 10.1093/cercor/bhx341

Tuning neural circuits by turning the interneuron knob

Dehorter, Nathalie, Marichal, Nicolás, Marín, Oscar and Berninger, Benedikt (2017). Tuning neural circuits by turning the interneuron knob. Current Opinion in Neurobiology, 42, 144-151. doi: 10.1016/j.conb.2016.12.009

Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch

Dehorter, Nathalie, Ciceri, Gabriele, Bartolini, Giorgia, Lim, Lynette, Del Pino, Isabel and Marín, Oscar (2015). Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch. Science, 349 (6253), 1216-1220. doi: 10.1126/science.aab3415

Giant GABAA receptor mediated currents in the striatum, a common signature of Parkinson's disease in pharmacological and genetic rodent models

Dehorter, Nathalie and Hammond, Constance (2014). Giant GABAA receptor mediated currents in the striatum, a common signature of Parkinson's disease in pharmacological and genetic rodent models. Basal Ganglia, 3 (4), 197-201. doi: 10.1016/j.baga.2013.10.001

Organization of interneurons lineages in the cerebral cortex Organisation des lignées d'interneurones du cortex cérébral

Ciceri, Gabriele and Dehorter, Nathalie (2014). Organization of interneurons lineages in the cerebral cortex Organisation des lignées d'interneurones du cortex cérébral. Medecine/Sciences, 30 (2), 144-146. doi: 10.1051/medsci/20143002010

Erbb4 Deletion from Fast-Spiking Interneurons Causes Schizophrenia-like Phenotypes

delPino, Isabel, García-Frigola, Cristina, Dehorter, Nathalie, Brotons-Mas, JorgeR., Alvarez-Salvado, Efrén, MartínezdeLagrán, María, Ciceri, Gabriele, Gabaldón, MaríaVictoria, Moratal, David, Dierssen, Mara, Canals, Santiago, Marín, Oscar and Rico, Beatriz (2013). Erbb4 Deletion from Fast-Spiking Interneurons Causes Schizophrenia-like Phenotypes. Neuron, 79 (6), 1152-1168. doi: 10.1016/j.neuron.2013.07.010

Lineage-specific laminar organization of cortical GABAergic interneurons

Ciceri, Gabriele, Dehorter, Nathalie, Sols, Ignasi, Huang, Z Josh, Maravall, Miguel and Marín, Oscar (2013). Lineage-specific laminar organization of cortical GABAergic interneurons. Nature Neuroscience, 16 (9), 1199-1210. doi: 10.1038/nn.3485

Subthalamic lesion or levodopa treatment rescues giant GABAergic currents of PINK1-deficient striatum

Dehorter, Nathalie, Lozovaya, Natalia, Julius Mdzomba, B., Michel, François J., Lopez, Catherine, Tsintsadze, Vera, Tsintsadze, Timur, Klinkenberg, Michael, Gispert, Suzanna, Auburger, Georg and Hammond, Constance (2012). Subthalamic lesion or levodopa treatment rescues giant GABAergic currents of PINK1-deficient striatum. Journal of Neuroscience, 32 (50), 18047-18053. doi: 10.1523/JNEUROSCI.2474-12.2012

Timing of developmental sequences in different brain structures: Physiological and pathological implications

Dehorter, N., Vinay, L., Hammond, C. and Ben-Ari, Y. (2012). Timing of developmental sequences in different brain structures: Physiological and pathological implications. European Journal of Neuroscience, 35 (12), 1846-1856. doi: 10.1111/j.1460-9568.2012.08152.x

Midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups

Ferrari, Diana C., Mdzomba, Baya J., Dehorter, Nathalie, Lopez, Catherine, Michel, François J., Libersat, Frédéric and Hammond, Constance (2012). Midbrain dopaminergic neurons generate calcium and sodium currents and release dopamine in the striatum of pups. Frontiers in Cellular Neuroscience (MARCH) 7, 1-9. doi: 10.3389/fncel.2012.00007

Onset of pup locomotion coincides with loss of NR2C/D-mediated cortico-striatal EPSCs and dampening of striatal network immature activity

Dehorter, Nathalie, Michel, François J., Marissal, Thomas, Rotrou, Yann, Matrot, Boris, Lopez, Catherine, Humphries, Mark D. and Hammond, Constance (2011). Onset of pup locomotion coincides with loss of NR2C/D-mediated cortico-striatal EPSCs and dampening of striatal network immature activity. Frontiers in Cellular Neuroscience (NOVEMBER), 1-14. doi: 10.3389/fncel.2011.00024

A wide diversity of cortical GABAergic interneurons derives from the embryonic preoptic area

Gelman, Diego, Griveau, Amélie, Dehorter, Nathalie, Teissier, Anne, Varela, Carolina, Pla, Ramón, Pierani, Alessandra and Marín, Oscar (2011). A wide diversity of cortical GABAergic interneurons derives from the embryonic preoptic area. Journal of Neuroscience, 31 (46), 16570-16580. doi: 10.1523/JNEUROSCI.4068-11.2011

Dopamine-deprived striatal GABAergic interneurons burst and generate repetitive gigantic IPSCs in medium spiny neurons

Dehorter, Nathalie, Guigoni, Celine, Lopez, Catherine, Hirsch, June, Eusebio, Alexandre, Ben-Ari, Yehezkel and Hammond, Constance (2009). Dopamine-deprived striatal GABAergic interneurons burst and generate repetitive gigantic IPSCs in medium spiny neurons. Journal of Neuroscience, 29 (24), 7776-7787. doi: 10.1523/JNEUROSCI.1527-09.2009

Brain-derived neurotrophic factor enhances fetal respiratory rhythm frequency in the mouse preBötzinger complex in vitro

Bouvier, Julien, Autran, Sandra, Dehorter, Nathalie, Katz, David M., Champagnat, Jean, Fortin, Gilles and Thoby-Brisson, Muriel (2008). Brain-derived neurotrophic factor enhances fetal respiratory rhythm frequency in the mouse preBötzinger complex in vitro. European Journal of Neuroscience, 28 (3), 510-520. doi: 10.1111/j.1460-9568.2008.06345.x