Ramanathan Yegappan is an early career researcher at the Australian Institute for Bioengineering and Nanotechnology (AIBN) at The University of Queensland (UQ). They completed their PhD in September 2023, focusing on understanding the science and application of snake venom proteins in wound healing. Ram has authored 8 research articles (4 as first author, 2 as co-first author) and 1 book chapter. These publications not only showcase their contributions to the field but also underscore their proficiency in conducting impactful research that translates into practical applications. In addition, they have also served as peer reviewer for journals and have reviewed over 30 research and review articles. Ram’s track record of honours and awards demonstrate their commitment to academic and research excellence, further enhancing his credibility as an emerging leader in this field.
In their current role, Ram manages multiple projects, conducting experiments at the interface of materials and cells, related to wound healing applications. They collaborate with researchers on project design, protocol preparation, data analysis and validation, statistical analysis and interpretation of findings, grant applications, and publications. Ram brings valuable expertise in the development and evaluation of next-generation biomaterials for wound healing applications, including the development of animal models for wound healing, in vivo evaluations, functional assays, as well as biochemical and histological evaluations. They have generated preliminary data for several grant proposals, and their foundational work formed the basis of two successful grants from the US Department of Defense and a CUREator, progressing the outcomes to preclinical stages.
Journal Article: The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents
Malone, Siobhan, Yegappan, Ramanathan, Kijas, Amanda, Gemmell, Anna, Rowan, Alan, Rajah, Divya, Kim, Minjun, Lauko, Jan and Amiralian, Nasim (2024). The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents. Polymers, 16 (12), 1654. doi: 10.3390/polym16121654
Other Outputs: Understanding the science and application of snake venom proteins in wound management
Ramanathan Yegappan, Ramanathan (2023). Understanding the science and application of snake venom proteins in wound management. PhD Thesis, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland. doi: 10.14264/0751854
Book Chapter: Carrageenan in tissue engineering and biomedical applications
Selvaprithiviraj, Vignesh, Yegappan, Ramanathan and Muthuswamy, Shiva (2023). Carrageenan in tissue engineering and biomedical applications. Natural biopolymers in drug delivery and tissue engineering. (pp. 449-480) edited by Rangasamy Jayakumar and Vishnu Priya Murali. Cambridge, MA United States: Woodhead Publishing. doi: 10.1016/b978-0-323-98827-8.00010-2
Carrageenan in tissue engineering and biomedical applications
Selvaprithiviraj, Vignesh, Yegappan, Ramanathan and Muthuswamy, Shiva (2023). Carrageenan in tissue engineering and biomedical applications. Natural biopolymers in drug delivery and tissue engineering. (pp. 449-480) edited by Rangasamy Jayakumar and Vishnu Priya Murali. Cambridge, MA United States: Woodhead Publishing. doi: 10.1016/b978-0-323-98827-8.00010-2
The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents
Malone, Siobhan, Yegappan, Ramanathan, Kijas, Amanda, Gemmell, Anna, Rowan, Alan, Rajah, Divya, Kim, Minjun, Lauko, Jan and Amiralian, Nasim (2024). The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents. Polymers, 16 (12), 1654. doi: 10.3390/polym16121654
Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation
Wang, Zhao, Lauko, Jan, Kijas, Amanda W., Gilbert, Elliot P., Turunen, Petri, Yegappan, Ramanathan, Zou, Dongxiu, Mata, Jitendra and Rowan, Alan E. (2023). Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation. Nature Communications, 14 (1) 1029, 1-16. doi: 10.1038/s41467-023-36437-9
Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding
Yegappan, Ramanathan, Lauko, Jan, Wang, Zhao, Lavin, Martin F., Kijas, Amanda W. and Rowan, Alan E. (2022). Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding. Advanced Healthcare Materials, 11 (15) 2200574, 2200574. doi: 10.1002/adhm.202200574
Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Mohandas, Annapoorna and Jayakumar, Rangasamy (2019). Nano polydopamine crosslinked thiol-functionalized hyaluronic acid hydrogel for angiogenic drug delivery. Colloids and Surfaces B-Biointerfaces, 177, 41-49. doi: 10.1016/j.colsurfb.2019.01.035
Injectable angiogenic and osteogenic carrageenan nanocomposite hydrogel for bone tissue engineering
Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Amirthalingam, Sivashanmugam, Mohandas, Annapoorna, Hwang, Nathaniel S. and Jayakumar, R. (2019). Injectable angiogenic and osteogenic carrageenan nanocomposite hydrogel for bone tissue engineering. International Journal of Biological Macromolecules, 122, 320-328. doi: 10.1016/j.ijbiomac.2018.10.182
Muthuswamy, Shiva, Viswanathan, Aparna, Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Vasudevan, Anil Kumar, Biswas, Raja and Jayakumar, Rangasamy (2019). Antistaphylococcal and neutrophil chemotactic injectable κ-carrageenan hydrogel for infectious wound healing. ACS Applied Bio Materials, 2 (1), 378-387. doi: 10.1021/acsabm.8b00625
Carrageenan based hydrogels for drug delivery, tissue engineering and wound healing
Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Amirthalingam, Sivashanmugam and Jayakumar, R. (2018). Carrageenan based hydrogels for drug delivery, tissue engineering and wound healing. Carbohydrate Polymers, 198, 385-400. doi: 10.1016/j.carbpol.2018.06.086
Jivan, Faraz, Yegappan, Ramanathan, Pearce, Hannah, Carrow, James K., McShane, Michael, Gaharwar, Akhilesh K. and Alge, Daniel L. (2016). Sequential thiol-ene and tetrazine click reactions for the polymerization and functionalization of hydrogel microparticles. Biomacromolecules, 17 (11), 3516-3523. doi: 10.1021/acs.biomac.6b00990
Understanding the science and application of snake venom proteins in wound management
Ramanathan Yegappan, Ramanathan (2023). Understanding the science and application of snake venom proteins in wound management. PhD Thesis, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland. doi: 10.14264/0751854