The University of Queensland

Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption

Williams, Scott A., Lay, Fung T., Bindra, Guneet K., Banjara, Suresh, Poon, Ivan K. H., Phan, Thanh Kha, Kvansakul, Marc and Hulett, Mark D. (2023). Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption. Nature Communications, 14 (1) 1170, 1-11. doi: 10.1038/s41467-023-36280-y

Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19

Islam, Saba, Charnley, Mirren, Bindra, Guneet, Ratcliffe, Julian, Zhou, Jiangtao, Mezzenga, Raffaele, Hulett, Mark, Han, Kyunghoon, Berryman, Joshua T., Reynolds, Nicholas P. and Engwirda, Jeremy (2022). Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19. Nature Communications, 13 (1) 3387, 1-11. doi: 10.1038/s41467-022-30932-1

Cytotoxic properties of rhenium(i) tricarbonyl complexes of N-heterocyclic carbene ligands

Wiratpruk, Nuchareenat, Bindra, Guneet K., Hamilton, Alex, Hulett, Mark D. and Barnard, Peter J. (2022). Cytotoxic properties of rhenium(i) tricarbonyl complexes of N-heterocyclic carbene ligands. Dalton Transactions, 51 (19), 7630-7643. doi: 10.1039/d2dt00447j

Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration

Bindra, Guneet K., Williams, Scott A., Lay, Fung T., Baxter, Amy A., Poon, Ivan K. H., Hulett, Mark D. and Phan, Thanh Kha (2022). Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration. Biomolecules, 12 (2) 264, 1-13. doi: 10.3390/biom12020264

Combating human pathogens and cancer by targeting phosphoinositides and their metabolism

Thanh Kha Phan,, Bindra, Guneet K., Williams, Scott A., Poon, Ivan K. H. and Hulett, Mark D. (2019). Combating human pathogens and cancer by targeting phosphoinositides and their metabolism. Trends in Pharmacological Sciences, 40 (11), 866-882. doi: 10.1016/j.tips.2019.09.006

Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death

Thanh Kha Phan,, Williams, Scott A., Bindra, Guneet K., Lay, Fung T., Poon, Ivan K. H. and Hulett, Mark D. (2019). Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death. Cell Death and Differentiation, 26 (5), 781-793. doi: 10.1038/s41418-018-0269-2

The crocodile defensin CpoBD13 defines a novel mechanism of host defence peptide antifungal activity through pH-dependent phospholipid targeting and membrane disruption

Williams, Scott A., Lay, Fung T., Bindra, Guneet K., Banjara, Suresh, Poon, Ivan K. H., Phan, Thanh Kha, Hulett, Mark D. and Kvansakul, Marc (2023). The crocodile defensin CpoBD13 defines a novel mechanism of host defence peptide antifungal activity through pH-dependent phospholipid targeting and membrane disruption. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323086618