The University of Queensland

Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients

Samimi, May N., Hale, Andrew, Schults, Jessica, Fischer, Andreas, Roberts, Jason A. and Dhanani, Jayesh (2024). Clinical guidance for unfractionated heparin dosing and monitoring in critically ill patients. Expert Opinion on Pharmacotherapy, ahead-of-print (ahead-of-print), 1-13. doi: 10.1080/14656566.2024.2364057

COVID-19 Drug Treatments Are Prone to Sequestration in Extracorporeal Membrane Oxygenation Circuits: An Ex Vivo Extracorporeal Membrane Oxygenation Study

Dhanani, Jayesh A., Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2024). COVID-19 Drug Treatments Are Prone to Sequestration in Extracorporeal Membrane Oxygenation Circuits: An Ex Vivo Extracorporeal Membrane Oxygenation Study. ASAIO journal (American Society for Artificial Internal Organs : 1992), 70 (6), 546-552. doi: 10.1097/MAT.0000000000002120

Cannabis use disorders and outcome of admission to intensive care: A retrospective multi-centre cohort study

Renger, Laura, Dhanani, Jayesh, Milford, Elissa, Tabah, Alexis, Shekar, Kiran, Ramanan, Mahesh and Laupland, Kevin B. (2024). Cannabis use disorders and outcome of admission to intensive care: A retrospective multi-centre cohort study. Journal of Critical Care, 80 154504, 154504. doi: 10.1016/j.jcrc.2023.154504

Delayed tracheoesophageal fistula and refractory respiratory failure caused by inhalation burns and emergency venovenous ECMO to facilitate its management: a case report

Dhanani, Jayesh, Pincus, Jason, Townsend, Shane, Pang, George, Vujcich, Elizabeth, Windsor, Morgan and Reade, Michael C. (2023). Delayed tracheoesophageal fistula and refractory respiratory failure caused by inhalation burns and emergency venovenous ECMO to facilitate its management: a case report. Journal of Burn Care and Research, 44 (3), 734-739. doi: 10.1093/jbcr/irad040

Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial

Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Doubrovsky, Anna, Parker, Suzanne L., Pintara, Alexander, Huygens, Flavia and Coyer, Fiona (2023). Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial. Intensive and Critical Care Nursing, 75 103364, 1-8. doi: 10.1016/j.iccn.2022.103364

Role of the emergency department in implementing an extracorporeal membrane oxygenation cardiopulmonary resuscitation

Gilbert, Felicity, Mitchell, Gary, Townsend, Shane, Dhanani, Jayesh and Sng, Nicole (2023). Role of the emergency department in implementing an extracorporeal membrane oxygenation cardiopulmonary resuscitation. EMA - Emergency Medicine Australasia, 35 (1), 173-175. doi: 10.1111/1742-6723.14100

Long duration anaesthesia in pigs with an infusion of alfaxalone and dexmedetomidine

Kat, Irving, Ahern, Benjamin J., Dhanani, Jayesh, Whitten, Grant, Cowling, Nicholas and Goodwin, Wendy (2022). Long duration anaesthesia in pigs with an infusion of alfaxalone and dexmedetomidine. Veterinary Medicine and Science, 8 (6), 2418-2421. doi: 10.1002/vms3.953

Optimising aerosolized therapies in critically ill patients

Dhanani, Jayesh, Taniguchi, Leandro U. and Ranzani, Otavio T. (2022). Optimising aerosolized therapies in critically ill patients. Intensive Care Medicine, 48 (10), 1418-1421. doi: 10.1007/s00134-022-06800-3

Nebulized antibiotics for healthcare- and ventilator-associated pneumonia

Boisson, Matthieu, Bouglé, Adrien, Sole-Lleonart, Candela, Dhanani, Jayesh, Arvaniti, Kostoula, Rello, Jordi, Rouby, Jean-Jacques and Mimoz, Olivier (2022). Nebulized antibiotics for healthcare- and ventilator-associated pneumonia. Seminars in Respiratory and Critical Care Medicine, 43 (2), 255-270. doi: 10.1055/s-0041-1740340

Determinants of research productivity during postgraduate medical education: a structured review

Laupland, Kevin B., Edwards, Felicity and Dhanani, Jayesh (2021). Determinants of research productivity during postgraduate medical education: a structured review. BMC Medical Education, 21 (1) 567, 567. doi: 10.1186/s12909-021-03010-1

Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report. International Journal of Antimicrobial Agents, 58 (5) 106431, 106431. doi: 10.1016/j.ijantimicag.2021.106431

Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study

Dhanani, Jayesh A., Goodman, Steven, Ahern, Benjamin, Cohen, Jeremy, Fraser, John F., Barnett, Adrian, Diab, Sara, Bhatt, Manoj and Roberts, Jason A. (2021). Comparative lung distribution of radiolabeled tobramycin between nebulized and intravenous administration in a mechanically-ventilated ovine model, an observational study. International Journal of Antimicrobial Agents, 57 (2) 106232, 106232. doi: 10.1016/j.ijantimicag.2020.106232

Octreotide for resuscitation of cardiac arrest due to carcinoid crisis precipitated by novel peptide receptor radionuclide therapy (PRRT): A case report

Dhanani, Jayesh, Pattison, David A., Burge, Matthew, Williams, Julian, Riedel, Bernhard, Hicks, Rodney J. and Reade, Michael C. (2020). Octreotide for resuscitation of cardiac arrest due to carcinoid crisis precipitated by novel peptide receptor radionuclide therapy (PRRT): A case report. Journal of Critical Care, 60, 319-322. doi: 10.1016/j.jcrc.2020.08.011

Pulmonary infections complicating ARDS

Luyt, Charles-Edouard, Bouadma, Lila, Morris, Andrew Conway, Dhanani, Jayesh A., Kollef, Marin, Lipman, Jeffrey, Martin-Loeches, Ignacio, Nseir, Saad, Ranzani, Otavio T., Roquilly, Antoine, Schmidt, Matthieu, Torres, Antoni and Timsit, Jean-François (2020). Pulmonary infections complicating ARDS. Intensive Care Medicine, 46 (12), 2168-2183. doi: 10.1007/s00134-020-06292-z

Increasing ventilator surge capacity in COVID 19 pandemic: design, manufacture and in vitro-in vivo testing in anaesthetized healthy pigs of a rapid prototyped mechanical ventilator

Dhanani, Jayesh, Pang, George, Pincus, Jason, Ahern, Benjamin, Goodwin, Wendy, Cowling, Nicholas, Whitten, Grant, Abdul-Aziz, Mohd H., Martin, Steven, Corke, Peter and Laupland, Kevin B. (2020). Increasing ventilator surge capacity in COVID 19 pandemic: design, manufacture and in vitro-in vivo testing in anaesthetized healthy pigs of a rapid prototyped mechanical ventilator. BMC Research Notes, 13 (1) 421, 421. doi: 10.1186/s13104-020-05259-z

Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model

Dhanani, Jayesh A., Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C., Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2020). Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model. Antimicrobial Agents and Chemotherapy, 64 (7) ARTN e02584-19. doi: 10.1128/aac.02584-19

Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report. Pharmacotherapy, 40 (7) phar.2413, 713-717. doi: 10.1002/phar.2413

Development and testing of a low cost simulation manikin for extracorporeal cardiopulmonary resuscitation (ECPR) using 3-dimensional printing

Pang, G., Futter, C., Pincus, J., Dhanani, J. and Laupland, K. B. (2020). Development and testing of a low cost simulation manikin for extracorporeal cardiopulmonary resuscitation (ECPR) using 3-dimensional printing. Resuscitation, 149, 24-29. doi: 10.1016/j.resuscitation.2020.01.032

Short‐ and long‐term outcomes of neutropenic cancer patients in intensive care according to requirement for invasive ventilation

Mackintosh, David, Way, Mandy, Reade, Michael C. and Dhanani, Jayesh (2019). Short‐ and long‐term outcomes of neutropenic cancer patients in intensive care according to requirement for invasive ventilation. Internal Medicine Journal, 50 (5) imj.14721, 603-611. doi: 10.1111/imj.14721

Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780

Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report. Chemotherapy, 64 (3), 1-4. doi: 10.1159/000502474

Nebulized tranexamic acid therapy for hemoptysis associated with submassive pulmonary embolism

Dhanani, Jayesh A., Roberts, Jason and Reade, Michael C (2019). Nebulized tranexamic acid therapy for hemoptysis associated with submassive pulmonary embolism. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 32 (1) jamp.2019.1534, 12-14. doi: 10.1089/jamp.2019.1534

Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model

Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019). Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 (2), 1-355. doi: 10.1097/ALN.0000000000002752

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review

Heffernan, Aaron J., Sime, Fekade B., Lipman, Jeffrey, Dhanani, Jayesh, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason A. (2019). Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review. International Journal of Antimicrobial Agents, 53 (3), 234-245. doi: 10.1016/j.ijantimicag.2018.11.011

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003

Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation

Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R. and Chan, Hak-Kim (2018). Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation. Pulmonary Pharmacology and Therapeutics, 50, 93-99. doi: 10.1016/j.pupt.2018.04.006

Strategies to reduce inappropriate laboratory blood test orders in intensive care are effective and safe: a before-and-after quality improvement study

Dhanani, J. A., Barnett, A. G., Lipman, J. and Reade, M. C. (2018). Strategies to reduce inappropriate laboratory blood test orders in intensive care are effective and safe: a before-and-after quality improvement study. Anaesthesia and Intensive Care, 46 (3), 313-320. doi: 10.1177/0310057X1804600309

Key considerations on nebulization of antimicrobial agents to mechanically ventilated patients

Rello, J., Rouby, J. J., Sole-Lleonart, C., Chastre, J., Blot, S., Luyt, C. E., Riera, J., Vos, M. C., Monsel, A., Dhanani, J. and Roberts, J. A. (2017). Key considerations on nebulization of antimicrobial agents to mechanically ventilated patients. Clinical Microbiology and Infection, 23 (9), 640-646. doi: 10.1016/j.cmi.2017.03.018

Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases

Rello, J., Sole-Lleonart, C., Rouby, J. -J., Chastre, J., Blot, S., Poulakou, G., Luyt, C. -E., Riera, J., Palmer, L. B., Pereira, J. M., Felton, T., Dhanani, J., Bassetti, M., Welte, T. and Roberts, J. A. (2017). Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases. Clinical Microbiology and Infection, 23 (9), 629-639. doi: 10.1016/j.cmi.2017.04.011

Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis

Sole-Lleonart, Candela, Rouby, Jean-Jacques, Blot, Stijn, Poulakou, Garyfallia, Chastre, Jean, Palmer, Lucy B., Bassetti, Matteo, Luyt, Charles-Edouard, Pereira, Jose M., Riera, Jordi, Felton, Tim, Dhanani, Jayesh, Welte, Tobias, Garcia-Alamino, Jose M., Roberts, Jason A. and Rello, Jordi (2017). Nebulization of antiinfective agents in invasively mechanically ventilated adults: a systematic review and meta-analysis. Anesthesiology, 126 (5), 890-908. doi: 10.1097/ALN.0000000000001570

A novel in-line delivery system to administer dry powder mannitol to mechanically ventilated patients

Feng, Benny, Tang, Patricia, Leung, Sharon Shui Yee, Dhanani, Jayesh and Chan, Hak-Kim (2017). A novel in-line delivery system to administer dry powder mannitol to mechanically ventilated patients. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 30 (2), 100-107. doi: 10.1089/jamp.2016.1320

Fundamentals of aerosol therapy in critical care

Dhanani, Jayesh, Fraser, John F., Chan, Hak-Kim, Rello, Jordi, Cohen, Jeremy and Roberts, Jason A. (2016). Fundamentals of aerosol therapy in critical care. Critical Care, 20 (1) 269, 269. doi: 10.1186/s13054-016-1448-5

Effect of preoperative renal function on long-term survival after cardiac surgery

Dhanani, Jayesh, Mullany, Daniel V. and Fraser, John F. (2013). Effect of preoperative renal function on long-term survival after cardiac surgery. Journal of Thoracic and Cardiovascular Surgery, 146 (1), 90-95. doi: 10.1016/j.jtcvs.2012.06.037

The dRTA-Rhabdomyolysis connection

Dhanani, J. A., McCarthy, J. and Fraser, J. F. (2012). The dRTA-Rhabdomyolysis connection. Anaesthesia and Intensive Care, 40 (4), 728-730.

Antibiotic therapy of pneumonia in critical care

Dhanani, Jayesg, Roberts, Jason A. and Lipman, Jeffrey (2012). Antibiotic therapy of pneumonia in critical care. Current Respiratory Medicine Reviews, 8 (3), 228-238. doi: 10.2174/157339812800493232

Antimicrobial chemotherapy and lung microdialysis: a review

Dhanani, Jayesh, Roberts, Jason A., Chew, Michelle, Lipman, Jeffrey, Boots, Robert J., Paterson, David L. and Fraser, John F. (2010). Antimicrobial chemotherapy and lung microdialysis: a review. International Journal of Antimicrobial Agents, 36 (6), 491-500. doi: 10.1016/j.ijantimicag.2010.08.013

Bedside prediction of central venous catheter insertion depth

Dhanani, J., Senthuran, S., Olivotto, R., Boots, R. J. and Lipman, J. (2007). Bedside prediction of central venous catheter insertion depth. British Journal of Anaesthesia, 98 (5), 695-695. doi: 10.1093/bja/aem080

The Entrapped Central Venous Catheter

Dhanani, J., Senthuran, S., Olivotto, R., Boots, R. J. and Lipman, J. (2007). The Entrapped Central Venous Catheter. British Journal of Anaesthesia, 98 (1), 89-92. doi: 10.1093/bja/ael286

Arterial catheter outcomes in intensive care: an analysis of 1117 patients

Keogh, Samantha, Larsen, Emily, Corley, Amanda, Takashima, Mari, Marsh, Nicole, Edwards, Melannie, Reynolds, Health, Dhanani, Jayesh, Coyer, Fiona, Laupland, Kevin and Rickard, Claire (2023). Arterial catheter outcomes in intensive care: an analysis of 1117 patients. 2023 ACIPC International Conference, Adelaide, SA Australia, 12-15 November 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2023.09.020

Evaluation of a closed loop blood sampling system in intensive care: A pilot randomised controlled trial. The enclose trial

Keogh, Samantha, Dhanani, Jayesh, Levido, Annabel, Gracie, Chris, Ilushin, Vladislav, Palmer, Jennifer, Parker, Suzanne, Doubrovsky, Anna, Hyugens, Flavia and Coyer, Fiona (2022). Evaluation of a closed loop blood sampling system in intensive care: A pilot randomised controlled trial. The enclose trial. ANZICS/ACCCN intensive care annual scientific meeting, Sydney, NSW Australia, 27-29 April 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.aucc.2022.08.015

Study of the disposition of nebulized tobramycin

Dhanani, Jayesh Anilkumar (2019). Study of the disposition of nebulized tobramycin. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/uql.2019.61