The University of Queensland

Rare variants are common in schizophrenia

Gratten, Jacob (2016). Rare variants are common in schizophrenia. Nature Neuroscience, 19 (11), 1426-1428. doi: 10.1038/nn.4422

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

Gratten, Jacob, Wray, Naomi R., Peyrot, Wouter J., McGrath, John J., Visscher, Peter M. and Goddard, Michael E. (2016). Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations. Nature Genetics, 48 (7), 718-+. doi: 10.1038/ng.3577

Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

Gratten, Jacob, Visscher, Peter M., Mowry, Bryan J. and Wray, Naomi R. (2013). Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease. Nature Genetics, 45 (3), 234-238. doi: 10.1038/ng.2555

Connecting clinical and genetic heterogeneity in ADHD

Yap, Chloe X. and Gratten, Jacob (2024). Connecting clinical and genetic heterogeneity in ADHD. Nature Genetics, 56 (2), 1-2. doi: 10.1038/s41588-024-01652-7

Connecting clinical and genetic heterogeneity in ADHD

Yap, Chloe X. and Gratten, Jacob (2024). Connecting clinical and genetic heterogeneity in ADHD. Nature Genetics, 56 (2), 195-196. doi: 10.1038/s41588-024-01652-7

Associations of the Gut Microbiome With Treatment Resistance in Schizophrenia

Vasileva, Svetlina S., Yang, Yuanhao, Baker, Andrea, Siskind, Dan, Gratten, Jacob and Eyles, Darryl (2024). Associations of the Gut Microbiome With Treatment Resistance in Schizophrenia. JAMA Psychiatry, 81 (3), 292-302. doi: 10.1001/jamapsychiatry.2023.5371

Erratum: Autism-related dietary preferences mediate autism-gut microbiome associations (Cell (2021) 184(24) (5916–5931.e17), (S0092867421012319), (10.1016/j.cell.2021.10.015))

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2024). Erratum: Autism-related dietary preferences mediate autism-gut microbiome associations (Cell (2021) 184(24) (5916–5931.e17), (S0092867421012319), (10.1016/j.cell.2021.10.015)). Cell, 187 (2), 495-510. doi: 10.1016/j.cell.2023.12.001

Association of number of siblings with preclinical markers of cardiovascular disease. The cardiovascular risk in Young Finns study

Pihlman, Jukka, Magnussen, Costan G., Laitinen, Tomi T., Ruohonen, Saku, Pahkala, Katja, Jokinen, Eero, Laitinen, Tomi P., Hutri-Kahonen, Nina, Tossavainen, Paivi, Taittonen, Leena, Kahonen, Mika, Viikari, Jorma SA., Raitakari, Olli T., Juonala, Markus and Nuotio, Joel (2023). Association of number of siblings with preclinical markers of cardiovascular disease. The cardiovascular risk in Young Finns study. International Journal of Cardiology Cardiovascular Risk and Prevention, 20 ARTN 200227, 200227. doi: 10.1016/j.ijcrp.2023.200227

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification

Kavousi, Maryam, Bos, Maxime M., Barnes, Hanna J., Cardenas, Christian L. Lino, Wong, Doris, Lu, Haojie, Hodonsky, Chani J., Landsmeer, Lennart P. L., Turner, Adam W., Kho, Minjung, Hasbani, Natalie R., de Vries, Paul S., Bowden, Donald W., Chopade, Sandesh, Deelen, Joris, Benavente, Ernest Diez, Guo, Xiuqing, Hofer, Edith, Hwang, Shih-Jen, Lutz, Sharon M., Lyytikaeinen, Leo-Pekka, Slenders, Lotte, Smith, Albert V., Stanislawski, Maggie A., van Setten, Jessica, Wong, Quenna, Yanek, Lisa R., Becker, Diane M., Beekman, Marian ... Miller, Clint L. (2023). Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification. Nature Genetics, 55 (10), 1651-1664. doi: 10.1038/s41588-023-01518-4

Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

Maury, Eduardo A., Sherman, Maxwell A., Genovese, Giulio, Gilgenast, Thomas G., Kamath, Tushar, Burris, S. J., Rajarajan, Prashanth, Flaherty, Erin, Akbarian, Schahram, Chess, Andrew, McCarroll, Steven A., Loh, Po-Ru, Phillips-Cremins, Jennifer E., Brennand, Kristen J., Macosko, Evan Z., Walters, James T.R., O'Donovan, Michael, Sullivan, Patrick, Marshall, Christian R., Merico, Daniele, Thiruvahindrapuram, Bhooma, Wang, Zhouzhi, Scherer, Stephen W., Howrigan, Daniel P, Ripke, Stephan, Bulik-Sullivan, Brendan, Farh, Kai-How, Fromer, Menachem, Goldstein, Jacqueline I. ... Walsh, Christopher A. (2023). Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions. Cell Genomics, 3 (8) 100356, 1-21. doi: 10.1016/j.xgen.2023.100356

Genetic insights into resting heart rate and its role in cardiovascular disease

van de Vegte, Yordi, Eppinga, Ruben P., van der Ende, M. Yldau, Hagemeijer, Yanick, Mahendran, Yuvaraj V., Salfati, Elias Y., Smith, Albert E., Tan, Vanessa, Arking, Dan V., Ntalla, Ioanna, Appel, Emil A., Schurmann, Claudia, Brody, Jennifer, Rueedi, Rico, Polasek, Ozren, Sveinbjornsson, Gardar, Lecoeur, Cecile, Ladenvall, Claes, Zhao, Jing Hua, Isaacs, Aaron, Wang, Lihua, Luan, Jian'an, Hwang, Shih-Jen, Mononen, Nina U., Auro, Kirsi F., Jackson, Anne, Bielak, Lawrence, Zeng, Linyao, Shah, Nabi ... van der Harst, Pim (2023). Genetic insights into resting heart rate and its role in cardiovascular disease. Nature Communications, 14 (1) 4646, 1-21. doi: 10.1038/s41467-023-39521-2

Polygenic liabilities underlying job stress and exhaustion over a 10-year follow-up: a general population study

Saarinen, Aino, Hietala, Jarmo, Lyytikainen, Leo-Pekka, Mishra, Binisha Hamal, Sormunen, Elina, Kahonen, Mika, Rovio, Suvi, Viikari, Jorma, Raitakari, Olli, Lehtimaki, Terho and Keltikangas-Jarvinen, Liisa (2023). Polygenic liabilities underlying job stress and exhaustion over a 10-year follow-up: a general population study. Psychiatry Research, 326 115355, 1-9. doi: 10.1016/j.psychres.2023.115355

Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

Hsu, Yu-Han H., Pintacuda, Greta, Liu, Ruize, Nacu, Eugeniu, Kim, April, Tsafou, Kalliopi, Petrossian, Natalie, Crotty, William, Suh, Jung Min, Riseman, Jackson, Martin, Jacqueline M., Biagini, Julia C., Mena, Daya, Ching, Joshua K.T., Malolepsza, Edyta, Li, Taibo, Singh, Tarjinder, Ge, Tian, Egri, Shawn B., Tanenbaum, Benjamin, Stanclift, Caroline R., Apffel, Annie M., Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T.R., Farh, Kai-How, Holmans, Peter A., Lee, Phil ... Lage, Kasper (2023). Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia. iScience, 26 (5) 106701, 1-28. doi: 10.1016/j.isci.2023.106701

Interactions between the lipidome and genetic and environmental factors in autism

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Giles, Corey, Huynh, Kevin, Nguyen, Anh, Wallace, Leanne, McLaren, Tiana, Yang, Yuanhao, Hernandez, Leanna M., Gandal, Michael J., Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Levis Frenk, Mira, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Strike, Lachlan T. ... The Busselton Health Study Investigators (2023). Interactions between the lipidome and genetic and environmental factors in autism. Nature Medicine, 29 (4), 936-949. doi: 10.1038/s41591-023-02271-1

The shared genetic landscape of blood cell traits and risk of neurological and psychiatric disorders

Yang, Yuanhao, Zhou, Yuan, Nyholt, Dale R., Yap, Chloe X., Tannenberg, Rudolph K., Wang, Ying, Wu, Yang, Zhu, Zhihong, Taylor, Bruce V. and Gratten, Jacob (2023). The shared genetic landscape of blood cell traits and risk of neurological and psychiatric disorders. Cell Genomics, 3 (2) 100249, 100249. doi: 10.1016/j.xgen.2022.100249

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, Vassily, Pardiñas, Antonio F, Qi, Ting, Panagiotaropoulou, Georgia, Awasthi, Swapnil, Bigdeli, Tim B, Bryois, Julien, Chen, Chia-Yen, Dennison, Charlotte A, Hall, Lynsey S, Lam, Max, Watanabe, Kyoko, Frei, Oleksandr, Ge, Tian, Harwood, Janet C, Koopmans, Frank, Magnusson, Sigurdur, Richards, Alexander L, Sidorenko, Julia, Wu, Yang, Zeng, Jian, Grove, Jakob, Kim, Minsoo, Li, Zhiqiang, Voloudakis, Georgios, Zhang, Wen, Adams, Mark, Agartz, Ingrid, Atkinson, Elizabeth G ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (2022). Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature, 604 (7906), 502-508. doi: 10.1038/s41586-022-04434-5

Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

Okbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A., Ahlskog, Rafael, Magnusson, Patrik K E, Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J., Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D., Johannesson, Magnus, Laibson, David, Meyer, Michelle N. ... Social Science Genetic Association Consortium (2022). Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals. Nature Genetics, 54 (4), 437-449. doi: 10.1038/s41588-022-01016-z

Australian Parkinson’s Genetics Study (APGS): pilot (n=1532)

Bivol, Svetlana, Mellick, George D., Gratten, Jacob, Parker, Richard, Mulcahy, Aoibhe, Mosley, Philip E., Poortvliet, Peter C., Campos, Adrian I., Mitchell, Brittany L., Garcia-Marin, Luis M., Cross, Simone, Ferguson, Mary, Lind, Penelope A., Loesch, Danuta Z., Visscher, Peter M., Medland, Sarah E., Scherzer, Clemens R., Martin, Nicholas G. and Rentería, Miguel E. (2022). Australian Parkinson’s Genetics Study (APGS): pilot (n=1532). BMJ Open, 12 (2) e052032, e052032. doi: 10.1136/bmjopen-2021-052032

Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases

Yang, Yuanhao, Musco, Hannah, Simpson-Yap, Steve, Zhu, Zhihong, Wang, Ying, Lin, Xin, Zhang, Jiawei, Taylor, Bruce, Gratten, Jacob and Zhou, Yuan (2021). Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases. Nature Communications, 12 (1) 5641, 5641. doi: 10.1038/s41467-021-25768-0

Autism-related dietary preferences mediate autism-gut microbiome associations

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2021). Autism-related dietary preferences mediate autism-gut microbiome associations. Cell, 184 (24), 5916-5931.e17. doi: 10.1016/j.cell.2021.10.015

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

Nabais, Marta F., Laws, Simon M., Lin, Tian, Vallerga, Costanza L., Armstrong, Nicola J., Blair, Ian P., Kwok, John B., Mather, Karen A., Mellick, George D., Sachdev, Perminder S., Wallace, Leanne, Henders, Anjali K., Zwamborn, Ramona A. J., Hop, Paul J., Lunnon, Katie, Pishva, Ehsan, Roubroeks, Janou A. Y., Soininen, Hilkka, Tsolaki, Magda, Mecocci, Patrizia, Lovestone, Simon, Kloszewska, Iwona, Vellas, Bruno, Furlong, Sarah, Garton, Fleur C., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee ... McRae, Allan F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22 (1) 90, 1-30. doi: 10.1186/s13059-021-02275-5

Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank

Yap, Chloe X., Alvares, Gail A., Henders, Anjali K., Lin, Tian, Wallace, Leanne, Farrelly, Alaina, McLaren, Tiana, Berry, Jolene, Vinkhuyzen, Anna A. E., Trzaskowski, Maciej, Zeng, Jian, Yang, Yuanhao, Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren, Leslie, Jodie, Levis Frenk, Mira, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Visscher, Peter M., Dawson, Paul A., Dissanayake, Cheryl ... Gratten, Jacob (2021). Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank. Molecular Autism, 12 (1) 12, 12. doi: 10.1186/s13229-020-00407-5

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

Vallerga, Costanza L., Zhang, Futao, Fowdar, Javed, McRae, Allan F., Qi, Ting, Nabais, Marta F., Zhang, Qian, Kassam, Irfahan, Henders, Anjali K., Wallace, Leanne, Montgomery, Grant, Chuang, Yu-Hsuan, Horvath, Steve, Ritz, Beate, Halliday, Glenda, Hickie, Ian, Kwok, John B., Pearson, John, Pitcher, Toni, Kennedy, Martin, Bentley, Steven R., Silburn, Peter A., Yang, Jian, Wray, Naomi R., Lewis, Simon J. G., Anderson, Tim, Dalrymple-Alford, John, Mellick, George D., Visscher, Peter M. and Gratten, Jacob (2020). Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease. Nature Communications, 11 (1) 1238, 1238. doi: 10.1038/s41467-020-15065-7

Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis

Nabais, Marta F., Lin, Tian, Benyamin, Beben, Williams, Kelly L., Garton, Fleur C., Vinkhuyzen, Anna A. E., Zhang, Futao, Vallerga, Costanza L., Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A. J., Hop, Paul J., Robinson, Matthew R., Gratten, Jacob, Visscher, Peter M., Hannon, Eilis, Mill, Jonathan, Brown, Matthew A., Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Needham, Merrilee, Veldink, Jan H., Mathers, Susan, Nicholson, Garth ... Wray, Naomi R. (2020). Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. npj Genomic Medicine, 5 (1) 10, 1-9. doi: 10.1038/s41525-020-0118-3

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Nalls, Mike A, Blauwendraat, Cornelis, Vallerga, Costanza L, Heilbron, Karl, Bandres-Ciga, Sara, Chang, Diana, Tan, Manuela, Kia, Demis A, Noyce, Alastair J, Xue, Angli, Bras, Jose, Young, Emily, von Coelln, Rainer, Simón-Sánchez, Javier, Schulte, Claudia, Sharma, Manu, Krohn, Lynne, Pihlstrøm, Lasse, Siitonen, Ari, Iwaki, Hirotaka, Leonard, Hampton, Faghri, Faraz, Gibbs, J Raphael, Hernandez, Dena G, Scholz, Sonja W, Botia, Juan A, Martinez, Maria, Corvol, Jean-Christophe, Lesage, Suzanne ... Zhang, Futao (2019). Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. The Lancet Neurology, 18 (12), 1091-1102. doi: 10.1016/S1474-4422(19)30320-5

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

Ahola-Olli, Ari V., Mustelin, Linda, Kalimeri, Maria, Kettunen, Johannes, Jokelainen, Jari, Auvinen, Juha, Puukka, Katri, Havulinna, Aki S., Lehtimaki, Terho, Kahonen, Mika, Juonala, Markus, Keinanen-Kiukaanniemi, Sirkka, Salomaa, Veikko, Perola, Markus, Jarvelin, Marjo-Riitta, Ala-Korpela, Mika, Raitakari, Olli and Wurtz, Peter (2019). Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts. Diabetologia, 62 (12), 2298-2309. doi: 10.1007/s00125-019-05001-w

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

Zhang, Qian, Vallerga, Costanza L., Walker, Rosie M., Lin, Tian, Henders, Anjali K., Montgomery, Grant W., He, Ji, Fan, Dongsheng, Fowdar, Javed, Kennedy, Martin, Pitcher, Toni, Pearson, John, Halliday, Glenda, Kwok, John B., Hickie, Ian, Lewis, Simon, Anderson, Tim, Silburn, Peter A., Mellick, George D., Harris, Sarah E., Redmond, Paul, Murray, Alison D., Porteous, David J., Haley, Christopher S., Evans, Kathryn L., McIntosh, Andrew M., Yang, Jian, Gratten, Jacob, Marioni, Riccardo E. ... Visscher, Peter M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11 (1) 54, 54. doi: 10.1186/s13073-019-0667-1

The genetic relationship between female reproductive traits and six psychiatric disorders

Ni, Guiyan, Amare, Azmeraw T., Zhou, Xuan, Mills, Natalie, Gratten, Jacob and Lee, S. Hong (2019). The genetic relationship between female reproductive traits and six psychiatric disorders. Scientific Reports, 9 (1) 12041, 12041. doi: 10.1038/s41598-019-48403-x

Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study

Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Vinkhuyzen, Anna, McRae, Allan, Holliday, Elizabeth G., Nyholt, Dale R., Nancarrow, Derek, Bakshi, Andrew, Hemani, Gibran, Nertney, Deborah, Smith, Heather, Filippich, Cheryl, Patel, Kalpana, Fowdar, Javed, McLean, Duncan, Tirupati, Srinivasan, Nagasundaram, Arunkumar, Gundugurti, Prasad Rao, Selvaraj, Krishnamurthy, Jegadeesan, Jayaprakash, Jorde, Lynn B., Wray, Naomi R., Brown, Matthew A., Suetani, Rachel, Giacomotto, Jean ... Mowry, Bryan J. (2019). Association of schizophrenia risk with disordered niacin metabolism in an Indian genome-wide association study. JAMA Psychiatry, 76 (10), 1026-1034. doi: 10.1001/jamapsychiatry.2019.1335

Parkinson's disease age at onset genome-wide association study: defining heritability, genetic loci, and α-synuclein mechanisms

Blauwendraat, Cornelis, Heilbron, Karl, Vallerga, Costanza L., Bandres-Ciga, Sara, von Coelln, Rainer, Pihlstrøm, Lasse, Simón-Sánchez, Javier, Schulte, Claudia, Sharma, Manu, Krohn, Lynne, Siitonen, Ari, Iwaki, Hirotaka, Leonard, Hampton, Noyce, Alastair J., Tan, Manuela, Gibbs, J. Raphael, Hernandez, Dena G., Scholz, Sonja W., Jankovic, Joseph, Shulman, Lisa M., Lesage, Suzanne, Corvol, Jean-Christophe, Brice, Alexis, van Hilten, Jacobus J., Marinus, Johan, Eerola-Rautio, Johanna, Tienari, Pentti, Majamaa, Kari, Toft, Mathias ... Singleton, Andrew B. (2019). Parkinson's disease age at onset genome-wide association study: defining heritability, genetic loci, and α-synuclein mechanisms. Movement Disorders, 34 (6) mds.27659, 866-875. doi: 10.1002/mds.27659

Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model trait

Chundru, V. Kartik, Marioni, Riccardo E., Prendergast, James G. D., Vallerga, Costanza L., Lin, Tian, Berveridge, Allan J., SGPD Consortium, Gratten, Jacob, Hume, David A., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2019). Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model trait. Genetics, 212 (3), 577-586. doi: 10.1534/genetics.118.301861

Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability

Reynolds, Regina H., Botia, Juan, Nalls, Mike A., Hardy, John, Taliun, Sarah A. Gagliano, Ryten, Mina, Noyce, Alastair J., Nicolas, Aude, Cookson, Mark R., Bandres-Ciga, Sara, Gibbs, J. Raphael, Hernandez, Dena G., Singleton, Andrew B., Reed, Xylena, Leonard, Hampton, Blauwendraat, Cornelis, Faghri, Faraz, Bras, Jose, Guerreiro, Rita, Tucci, Arianna, Kia, Demis A., Houlden, Henry, Plun-Favreau, Helene, Mok, Kin Y., Wood, Nicholas W., Lovering, Ruth, R'Bibo, Lea, Rizig, Mie, Chelban, Viorica ... Pearson, John (2019). Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability. Npj Parkinsons Disease, 5 (1) 6, 6. doi: 10.1038/s41531-019-0076-6

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M. ... Beauchamp, Jonathan P. (2019). Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nature Genetics, 51 (2), 245-257. doi: 10.1038/s41588-018-0309-3

The <i>rs2516839</i> variation of <i>USF1</i> gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+study

Ozsait-Selcuk, B., Komurcu-Bayrak, E., Jylha, M., Luukkaala, T., Perola, M., Kristiansson, K., Mononen, N., Hurme, M., Kahonen, M., Goebeler, S., Laaksonen, R., Hervonen, A., Erginel-Unaltuna, N., Karhunen, P. J. and Lehtimaki, T. (2019). The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+study. Annals of Human Genetics, 83 (1), 34-45. doi: 10.1111/ahg.12282

Imprint of assortative mating on the human genome

Yengo, Loic, Robinson, Matthew R., Keller, Matthew C., Kemper, Kathryn E., Yang, Yuanhao, Trzaskowski, Maciej, Gratten, Jacob, Turley, Patrick, Cesarini, David, Benjamin, Daniel J., Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2018). Imprint of assortative mating on the human genome. Nature Human Behaviour, 2 (12), 948-954. doi: 10.1038/s41562-018-0476-3

Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

Alvares, Gail A., Dawson, Paul A., Dissanayake, Cheryl, Eapen, Valsamma, Gratten, Jacob, Grove, Rachel, Henders, Anjali, Heussler, Helen, Lawson, Lauren, Masi, Anne, Raymond, Emma, Rose, Felicity, Wallace, Leanne, Wray, Naomi R. and Whitehouse, Andrew J. O. (2018). Study protocol for the Australian autism biobank: an international resource to advance autism discovery research. BMC Pediatrics, 18 (1) 284, 284. doi: 10.1186/s12887-018-1255-z

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, Guiyan, Gratten, Jacob, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R. and Lee, Sang Hong (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports, 8 (1) 10168, 10168. doi: 10.1038/s41598-018-28160-z

Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis

Bhosale, Santosh D., Moulder, Robert, Venalainen, Mikko S., Koskinen, Juhani S., Pitkanen, Niina, Juonala, Markus T., Kahonen, Mika A. P., Lehtimaki, Terho J., Viikari, Jorma S. A., Elo, Laura L., Goodlett, David R., Lahesmaa, Riitta and Raitakari, Olli T. (2018). Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis. Scientific Reports, 8 (1) ARTN 9209. doi: 10.1038/s41598-018-27265-9

Trans-eQTLs identified in whole blood have limited influence on complex disease biology

Yap, Chloe X., Lloyd-Jones, Luke, Holloway, Alexander, Smartt, Peter, Wray, Naomi R., Gratten, Jacob and Powell, Joseph E. (2018). Trans-eQTLs identified in whole blood have limited influence on complex disease biology. European Journal of Human Genetics, 26 (9), 1-8. doi: 10.1038/s41431-018-0174-7

Sizing up whole-genome sequencing studies of common diseases

Wray, Naomi R. and Gratten, Jacob (2018). Sizing up whole-genome sequencing studies of common diseases. Nature Genetics, 50 (5), 635-637. doi: 10.1038/s41588-018-0113-0

Gene networks associated with non-syndromic intellectual disability

Lee, Soohyun, Rudd, Stephen, Gratten, Jacob, Visscher, Peter M., Prins, Johannes B. and Dawson, Paul A. (2017). Gene networks associated with non-syndromic intellectual disability. Journal of Neurogenetics, 32 (1), 6-14. doi: 10.1080/01677063.2017.1404058

Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese

Gratten, Jacob, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul J., Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jin, Zi-Bing, Li, Zhongshan, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, Mowry, Bryan J., Ran, Shu, Reutens, David C., Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn H. ... Fan, Dongsheng (2017). Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Medicine, 9 (97) 97, 97. doi: 10.1186/s13073-017-0487-0

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

Benyamin, Beben, He, Ji, Zhao, Qiongyi, Gratten, Jacob, Garton, Fleur, Leo, Paul J., Liu, Zhijun, Mangelsdorf, Marie, Al-Chalabi, Ammar, Anderson, Lisa, Butler, Timothy J., Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Devine, Matthew, Edson, Janette, Fifita, Jennifer A., Furlong, Sarah, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jeffree, Rosalind L., Jin, Zi-Bing, Li, Zhongshan, Li, Ting, Li, Mengmeng, Lin, Yong, Liu, Xiaolu ... Fan, Dongsheng (2017). Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nature Communications, 8 (1) 611, 611. doi: 10.1038/s41467-017-00471-1

Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort

Garton, Fleur C., Benyamin, Beben, Zhao, Qiongyi, Liu, Zhijun, Gratten, Jacob, Henders, Anjali K., Zhang, Zong-Hong, Edson, Janette, Furlong, Sarah, Morgan, Sarah, Heggie, Susan, Thorpe, Kathryn, Pfluger, Casey, Mather, Karen A., Sachdev, Perminder S., McRae, Allan F., Robinson, Matthew R., Shah, Sonia, Visscher, Peter M., Mangelsdorf, Marie, Henderson, Robert D., Wray, Naomi R. and McCombe, Pamela A. (2017). Whole exome sequencing and DNA methylation analysis in a clinical amyotrophic lateral sclerosis cohort. Molecular Genetics and Genomic Medicine, 5 (4), 418-428. doi: 10.1002/mgg3.302

Rare variants are common in schizophrenia

Gratten, Jacob (2016). Rare variants are common in schizophrenia. Nature Neuroscience, 19 (11), 1426-1428. doi: 10.1038/nn.4422

Genome-wide associations for birth weight and correlations with adult disease

Horikoshi, Momoko, Beaumont, Robin N., Day, Felix R., Warrington, Nicole M., Kooijman, Marjolein N., Fernandez-Tajes, Juan, Feenstra, Bjarke, van Zuydam, Natalie R., Gaulton, Kyle J., Grarup, Niels, Bradfield, Jonathan P., Strachan, David P., Li-Gao, Ruifang, Ahluwalia, Tarunveer S., Kreiner, Eskil, Rueedi, Rico, Lyytikainen, Leo-Pekka, Cousminer, Diana L., Wu, Ying, Thiering, Elisabeth, Wang, Carol A., Have, Christian T., Hottenga, Jouke-Jan, Vilor-Tejedor, Natalia, Joshi, Peter K., Boh, Eileen Tai Hui, Ntalla, Ioanna, Pitkanen, Niina, Mahajan, Anubha ... Freathy, Rachel M. (2016). Genome-wide associations for birth weight and correlations with adult disease. Nature, 538 (7624), 248-252. doi: 10.1038/nature19806

Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

Pavlides, Jennifer M. Whitehead, Zhu, Zhihong, Gratten, Jacob, Mcrae, Allan F., Wray, Naomi R. and Yang, Jian (2016). Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. Genome Medicine, 8 (1) 84, 84. doi: 10.1186/s13073-016-0338-4

Genetic pleiotropy in complex traits and diseases: implications for genomic medicine

Gratten, Jacob and Visscher, Peter M. (2016). Genetic pleiotropy in complex traits and diseases: implications for genomic medicine. Genome Medicine, 8 (78) 78, 1-3. doi: 10.1186/s13073-016-0332-x

Childhood Infections, Socioeconomic Status, and Adult Cardiometabolic Risk

Liu, Richard S., Burgner, David P., Sabin, Matthew A., Magnussen, Costan G., Cheung, Michael, Hutri-Kahonen, Nina, Kahonen, Mika, Lehtimaki, Terho, Jokinen, Eero, Laitinen, Tomi, Taittonen, Leena, Dwyer, Terence, Viikari, Jorma S. A., Kivimaki, Mika, Raitakari, Olli T. and Juonala, Markus (2016). Childhood Infections, Socioeconomic Status, and Adult Cardiometabolic Risk. Pediatrics, 137 (6) ARTN e20160236. doi: 10.1542/peds.2016-0236

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Okbay, Aysu, Baselmans, Bart M. L., De Neve, Jan-Emmanuel, Turley, Patrick, Nivard, Michel G., Fontana, Mark Alan, Meddens, S. Fleur W., Linner, Richard Karlsson, Rietveld, Cornelius A., Derringer, Jaime, Gratten, Jacob, Lee, James J., Liu, Jimmy Z., de Vlaming, Ronald, Ahluwalia, Tarunveer S., Buchwald, Jadwiga, Cavadino, Alana, Frazier-Wood, Alexis C., Furlotte, Nicholas A., Garfield, Victoria, Geisel, Marie Henrike, Gonzalez, Juan R., Haitjema, Saskia, Karlsson, Robert, van der Laan, Sander W., Ladwig, Karl-Heinz, Lahti, Jari, van der Lee, Sven J., Lind, Penelope A. ... Cesarini, David (2016). Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics, 48 (6), 624-633. doi: 10.1038/ng.3552

International genome-wide association study consortium identifies novel loci associated with blood pressure in children and adolescents

Parmar, Priyakumari Ganesh, Taal, H. Rob, Timpson, Nicholas J., Thiering, Elisabeth, Lehtimaki, Terho, Marinelli, Marcella, Lind, Penelope A., Howe, Laura D., Verwoert, Germaine, Aalto, Ville, Uitterlinden, Andre G., Briollais, Laurent, Evans, Dave M., Wright, Margie J., Newnham, John P., Whitfield, John B., Lyytikainen, Leo-Pekka, Rivadeneira, Fernando, Boomsma, Dorrett I., Viikari, Jorma, Gillman, Matthew W., St Pourcain, Beate, Hottenga, Jouke-Jan, Montgomery, Grant W., Hofman, Albert, Kahonen, Mika, Martin, Nicholas G., Tobin, Martin D., Raitakari, Ollie ... Palmer, Lyle J. (2016). International genome-wide association study consortium identifies novel loci associated with blood pressure in children and adolescents. Circulation: Cardiovascular Genetics, 9 (3), 266-278. doi: 10.1161/CIRCGENETICS.115.001190

Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations

Gratten, Jacob, Wray, Naomi R., Peyrot, Wouter J., McGrath, John J., Visscher, Peter M. and Goddard, Michael E. (2016). Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations. Nature Genetics, 48 (7), 718-+. doi: 10.1038/ng.3577

Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, Aysu, Beauchamp, Jonathan P., Fontana, Mark Alan, Lee, James J., Pers, Tune H., Rietveld, Cornelius A., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S. Fleur W., Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Furlotte, Nicholas A., Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E. ... Benjamin, Daniel J. (2016). Genome-wide association study identifies 74 loci associated with educational attainment. Nature, 533 (7604), 539-542. doi: 10.1038/nature17671

Childhood Psychosocial Factors and Coronary Artery Calcification in Adulthood The Cardiovascular Risk in Young Finns Study

Juonala, Markus, Pulkki-Raback, Laura, Elovainio, Marko, Hakulinen, Christian, Magnussen, Costan G., Sabin, Matthew A., Burgner, David P., Hare, David L., Hartiala, Olli, Ukkonen, Heikki, Saraste, Antti, Kajander, Sami, Hutri-Kahonen, Nina, Kahonen, Mika, Rinta-Kiikka, Irina, Laitinen, Tomi, Kainulainen, Sakari, Viikari, Jorma S. A. and Raitakari, Olli T. (2016). Childhood Psychosocial Factors and Coronary Artery Calcification in Adulthood The Cardiovascular Risk in Young Finns Study. Jama Pediatrics, 170 (5), 466-472. doi: 10.1001/jamapediatrics.2015.4121

Evidence for genetic overlap between schizophrenia and age at first birth in women

Mehta, Divya, Tropf, Felix C., Gratten, Jacob, Bakshi, Andrew, Zhu, Zhihong, Bacanu, Silviu-Alin, Hemani, Gibran, Magnusson, Patrik K. E., Barban, Nicola, Esko, Tonu, Metspalu, Andres, Snieder, Harold, Mowry, Bryan J., Kendler, Kenneth S., Yang, Jian, Visscher, Peter M., McGrath, John J., Mills, Melinda C., Wray, Naomi R. and Lee, S. Hong (2016). Evidence for genetic overlap between schizophrenia and age at first birth in women. Jama Psychiatry, 73 (5), 497-505. doi: 10.1001/jamapsychiatry.2016.0129

Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulation

Ragan, Chikako, Patel, Kalpana, Edson, Janette, Zhang, Zong-Hong, Gratten, Jacob and Mowry, Bryan (2016). Small non-coding RNA expression from anterior cingulate cortex in schizophrenia shows sex specific regulation. Schizophrenia Research, 183, 82-87. doi: 10.1016/j.schres.2016.11.024

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses

Aho, Vilma, Ollila, Hanna M., Kronholm, Erkki, Bondia-Pons, Isabel, Soininen, Pasi, Kangas, Antti J., Hilvo, Mika, Seppala, Ilkka, Kettunen, Johannes, Oikonen, Mervi, Raitoharju, Emma, Hyotylainen, Tuulia, Kahonen, Mika, Viikari, Jorma S. A., Harma, Mikko, Sallinen, Mikael, Olkkonen, Vesa M., Alenius, Harri, Jauhiainen, Matti, Paunio, Tiina, Lehtimaki, Terho, Salomaa, Veikko, Oresic, Matej, Raitakari, Olli T., Ala-Korpela, Mika and Porkka-Heiskanen, Tarja (2016). Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses. Scientific Reports, 6 (1) ARTN 24828. doi: 10.1038/srep24828

Continuous and Dichotomous Metabolic Syndrome Definitions in Youth Predict Adult Type 2 Diabetes and Carotid Artery Intima Media Thickness: The Cardiovascular Risk in Young Finns Study

Magnussen, Costan G., Cheriyan, Sanith, Sabin, Matthew A., Juonala, Markus, Koskinen, Juha, Thomson, Russell, Skilton, Michael R., Kahonen, Mika, Laitinen, Tomi, Taittonen, Leena, Hutri-Kahonen, Nina, Viikari, Jorma S. A. and Raitakari, Olli T. (2016). Continuous and Dichotomous Metabolic Syndrome Definitions in Youth Predict Adult Type 2 Diabetes and Carotid Artery Intima Media Thickness: The Cardiovascular Risk in Young Finns Study. Journal of Pediatrics, 171, 97-+. doi: 10.1016/j.jpeds.2015.10.093

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke

Seppala, Ilkka, Kleber, Marcus E., Bevan, Steve, Lyytikainen, Leo-Pekka, Oksala, Niku, Hernesniemi, Jussi A., Makela, Kari-Matti, Rothwell, Peter M., Sudlow, Cathie, Dichgans, Martin, Mononen, Nina, Vlachopoulou, Efthymia, Sinisalo, Juha, Delgado, Graciela E., Laaksonen, Reijo, Koskinen, Tuomas, Scharnagl, Hubert, Kahonen, Mika, Markus, Hugh S., Marz, Winfried and Lehtimaki, Terho (2016). Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke. Scientific Reports, 6 ARTN 23207. doi: 10.1038/srep23207

Mapping and differential expression analysis from short-read RNA-Seq data in model organisms

Zhao, Qiong-Yi, Gratten, Jacob, Restaudi, Restuadi and Li, Xuan (2016). Mapping and differential expression analysis from short-read RNA-Seq data in model organisms. Quantitative Biology, 4 (1), 22-35. doi: 10.1007/s40484-016-0060-7

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

Felix, Janine F., Bradfield, Jonathan P., Monnereau, Claire, van der Valk, Ralf J. P., Stergiakouli, Evie, Chesi, Alessandra, Gaillard, Romy, Feenstra, Bjarke, Thiering, Elisabeth, Kreiner-Moller, Eskil, Mahajan, Anubha, Pitkanen, Niina, Joro, Raimo, Cavadino, Alana, Huikari, Ville, Franks, Steve, Groen-Blokhuis, Maria M., Cousminer, Diana L., Marsh, Julie A., Lehtimaki, Terho, Curtin, John A., Vioque, Jesus, Ahluwalia, Tarunveer S., Myhre, Ronny, Price, Thomas S., Vilor-Tejedor, Natalia, Yengo, Loic, Grarup, Niels, Ntalla, Ioanna ... Jaddoe, Vincent W. V. (2016). Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics, 25 (2), 389-403. doi: 10.1093/hmg/ddv472

Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study

Hartiala, Olli, Magnussen, Costan G., Bucci, Marco, Kajander, Sami, Knuuti, Juhani, Ukkonen, Heikki, Saraste, Antti, Rinta-Kiikka, Irina, Kainulainen, Sakari, Kahonen, Mika, Hutri-Kahonen, Nina, Laitinen, Tomi, Lehtimaki, Terho, Viikari, Jorma S. A., Hartiala, Jaakko, Juonala, Markus and Raitakari, Olli T. (2015). Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study. European Heart Journal-Cardiovascular Imaging, 16 (11), 1256-1263. doi: 10.1093/ehjci/jev085

Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery Criteria

Juonala, Markus, Sabin, Matthew A., Burgner, David, Cheung, Michael, Kahonen, Mika, Hutri-Kahonen, Nina, Lehtimaki, Terho, Jokinen, Eero, Koskinen, Juha, Tossavainen, Paivi, Laitinen, Tomi, Viikari, Jorma S. A., Raitakari, Olli T. and Magnussen, Costan G. (2015). Increased Body Mass Index in Parent-Child Dyads Predicts the Offspring Risk of Meeting Bariatric Surgery Criteria. Journal of Clinical Endocrinology & Metabolism, 100 (11), 4257-4263. doi: 10.1210/jc.2015-2524

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

Ritchie, Scott C., Wurtz, Peter, Nath, Artika P., Abraham, Gad, Havulinna, Aki S., Fearnley, Liam G., Sarin, Antti-Pekka, Kangas, Antti J., Soininen, Pasi, Aalto, Kristiina, Seppala, Ilkka, Raitoharju, Emma, Salmi, Marko, Maksimow, Mikael, Mannisto, Satu, Kahonen, Mika, Juonala, Markus, Ripatti, Samuli, Lehtimaki, Terho, Jalkanen, Sirpa, Perola, Markus, Raitakari, Olli, Salomaa, Veikko, Ala-Korpela, Mika, Kettunen, Johannes and Inouye, Michael (2015). The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection. Cell Systems, 1 (4), 293-301. doi: 10.1016/j.cels.2015.09.007

Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study

Arnott, Clare, Skilton, Michael R., Ruohonen, Saku, Juonala, Markus, Viikari, Jorma S. A., Kahonen, Mika, Lehtimaki, Terho, Laitinen, Tomi, Celermajer, David S. and Raitakari, Olli T. (2015). Subtle increases in heart size persist into adulthood in growth restricted babies: the Cardiovascular Risk in Young Finns Study. Open Heart, 2 (1) UNSP e000265, e000265. doi: 10.1136/openhrt-2015-000265

The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study

Winkler, Thomas W., Justice, Anne E., Graff, Mariaelisa, Barata, Llilda, Feitosa, Mary F., Chu, Su, Czajkowski, Jacek, Esko, Tonu, Fall, Tove, Kilpelainen, Tuomas O., Lu, Yingchang, Magi, Reedik, Mihailov, Evelin, Pers, Tune H., Rueeger, Sina, Teumer, Alexander, Ehret, Georg B., Ferreira, Teresa, Heard-Costa, Nancy L., Karjalainen, Juha, Lagou, Vasiliki, Mahajan, Anubha, Neinast, Michael D., Prokopenko, Inga, Simino, Jeannette, Teslovich, Tanya M., Jansen, Rick, Westra, Harm-Jan, White, Charles C. ... Loos, Ruth J. F. (2015). The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study. PL o S Genetics, 11 (10) e1005378, 1-42. doi: 10.1371/journal.pgen.1005378

Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns Study

Juonala, Markus, Cheung, Michael M. H., Sabin, Matthew A., Burgner, David, Skilton, Michael R., Kahonen, Mika, Hutri-Kahonen, Nina, Lehtimaki, Terho, Jula, Antti, Laitinen, Tomi, Jokinen, Eero, Taittonen, Leena, Tossavainen, Paivi, Viikari, Jorma S. A., Magnussen, Costan G. and Raitakari, Olli T. (2015). Effect of birth weight on life-course blood pressure levels among children born premature: the Cardiovascular Risk in Young Finns Study. Journal of Hypertension, 33 (8), 1542-1548. doi: 10.1097/HJH.0000000000000612

Vigorous physical activity and carotid distensibility in young and mid-aged adults

Huynh, Quan L., Blizzard, Christopher L., Raitakari, Olli, Sharman, James E., Magnussen, Costan G., Dwyer, Terence, Juonala, Markus, Kahonen, Mika and Venn, Alison J. (2015). Vigorous physical activity and carotid distensibility in young and mid-aged adults. Hypertension Research, 38 (5), 355-360. doi: 10.1038/hr.2015.9

Lifetime measures of ideal cardiovascular health and their association with subclinical atherosclerosis: The Cardiovascular Risk in Young Finns Study

Laitinen, Tomi T., Pahkala, Katja, Magnussen, Costan G., Oikonen, Mervi, Viikari, Jorma S. A., Sabin, Matthew A., Daniels, Stephen R., Heinonen, Olli J., Taittonen, Leena, Hartiala, Olli, Mikkila, Vera, Hutri-Kahonen, Nina, Laitinen, Tomi, Kahonen, Mika, Raitakari, Olli T. and Juonala, Markus (2015). Lifetime measures of ideal cardiovascular health and their association with subclinical atherosclerosis: The Cardiovascular Risk in Young Finns Study. International Journal of Cardiology, 185, 186-191. doi: 10.1016/j.ijcard.2015.03.051

Exposure to Parental Smoking in Childhood Is Associated With Increased Risk of Carotid Atherosclerotic Plaque in Adulthood The Cardiovascular Risk in Young Finns Study

West, Henry W., Juonala, Markus, Gall, Seana L., Kahonen, Mika, Laitinen, Tomi, Taittonen, Leena, Viikari, Jorma S. A., Raitakari, Olli T. and Magnussen, Costan G. (2015). Exposure to Parental Smoking in Childhood Is Associated With Increased Risk of Carotid Atherosclerotic Plaque in Adulthood The Cardiovascular Risk in Young Finns Study. Circulation, 131 (14), 1239-1246. doi: 10.1161/CIRCULATIONAHA.114.013485

Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study

Juonala, Markus, Voipio, Atte, Pahkala, Katja, Viikari, Jorma S. A., Mikkila, Vera, Kahonen, Mika, Hutri-Kahonen, Nina, Jula, Antti, Burgner, David, Sabin, Matthew A., Marniemi, Jukka, Loo, Britt-Marie, Laitinen, Tomi, Jokinen, Eero, Taittonen, Leena, Magnussen, Costan G. and Raitakari, Olli T. (2015). Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study. Journal of Clinical Endocrinology & Metabolism, 100 (4), 1469-1476. doi: 10.1210/jc.2014-3944

Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: The Cardiovascular Risk in Young Finns Study

Burgner, David P., Sabin, Matthew A., Magnussen, Costan G., Cheung, Michael, Sun, Cong, Kahonen, Mika, Hutri-Kahonen, Nina, Lehtimaki, Terho, Jokinen, Eero, Laitinen, Tomi, Viikari, Jorma S. A., Raitakari, Olli T. and Juonala, Markus (2015). Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: The Cardiovascular Risk in Young Finns Study. Atherosclerosis, 239 (2), 496-502. doi: 10.1016/j.atherosclerosis.2015.02.024

Heterogeneity of genetic architecture of body size traits in a free-living population

Berenos, Camillo, Ellis, Philip A., Pilkington, Jill G., Lee, S. Hong, Gratten, Jake and Pemberton, Josephine M. (2015). Heterogeneity of genetic architecture of body size traits in a free-living population. Molecular Ecology, 24 (8), 1810-1830. doi: 10.1111/mec.13146

Insulin and BMI as Predictors of Adult Type 2 Diabetes Mellitus

Sabin, Matthew A., Magnussen, Costan G., Juonala, Markus, Shield, Julian P. H., Kahonen, Mika, Lehtimaki, Terho, Ronnemaa, Tapani, Koskinen, Juha, Loo, Britt-Marie, Knip, Mikael, Hutri-Kahonen, Nina, Viikari, Jorma S. A., Dwyer, Terence and Raitakari, Olli T. (2015). Insulin and BMI as Predictors of Adult Type 2 Diabetes Mellitus. Pediatrics, 135 (1), E144-E151. doi: 10.1542/peds.2014-1534

Cardiovascular risk factors in 2011 and secular trends since 2007: The Cardiovascular Risk in Young Finns Study

Nuotio, Joel, Oikonen, Mervi, Magnussen, Costan G., Jokinen, Eero, Laitinen, Tomi, Hutri-Kahonen, Nina, Kahonen, Mika, Lehtimaki, Terho, Taittonen, Leena, Tossavainen, Paivi, Jula, Antti, Loo, Britt-Marie, Viikari, Jorma S. A., Raitakari, Olli T. and Juonala, Markus (2014). Cardiovascular risk factors in 2011 and secular trends since 2007: The Cardiovascular Risk in Young Finns Study. Scandinavian Journal of Public Health, 42 (7), 563-571. doi: 10.1177/1403494814541597

Exposure to parental smoking in childhood or adolescence is associated with increased carotid intima-media thickness in young adults: evidence from the Cardiovascular Risk in Young Finns study and the Childhood Determinants of Adult Health Study

Gall, Seana, Quan Long Huynh, , Magnussen, Costan G., Juonala, Markus, Viikari, Jorma S. A., Kahonen, Mika, Dwyer, Terence, Raitakari, Olli T. and Venn, Alison (2014). Exposure to parental smoking in childhood or adolescence is associated with increased carotid intima-media thickness in young adults: evidence from the Cardiovascular Risk in Young Finns study and the Childhood Determinants of Adult Health Study. European Heart Journal, 35 (36), 2484-2491. doi: 10.1093/eurheartj/ehu049

High Birth Weight Is Associated With Obesity and Increased Carotid Wall Thickness in Young Adults The Cardiovascular Risk in Young Finns Study

Skilton, Michael R., Siitonen, Niina, Wuertz, Peter, Viikari, Jorma S. A., Juonala, Markus, Seppaelae, Ilkka, Laitinen, Tomi, Lehtimaeki, Terho, Taittonen, Leena, Kaehoenen, Mika, Celermajer, David S. and Raitakari, Olli T. (2014). High Birth Weight Is Associated With Obesity and Increased Carotid Wall Thickness in Young Adults The Cardiovascular Risk in Young Finns Study. Arteriosclerosis Thrombosis and Vascular Biology, 34 (5), 1064-1068. doi: 10.1161/ATVBAHA.113.302934

Association of Physical Activity in Childhood and Early Adulthood With Carotid Artery Elasticity 21 Years Later: The Cardiovascular Risk in Young Finns Study

Palve, Kristiina S., Pahkala, Katja, Magnussen, Costan G., Koivistoinen, Teemu, Juonala, Markus, Kahonen, Mika, Lehtimaki, Terho, Ronnemaa, Tapani, Viikari, Jorma S. A. and Raitakari, Olli T. (2014). Association of Physical Activity in Childhood and Early Adulthood With Carotid Artery Elasticity 21 Years Later: The Cardiovascular Risk in Young Finns Study. Journal of the American Heart Association, 3 (2) ARTN e000594. doi: 10.1161/JAHA.113.000594

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Catts, Stanley V., Gratten, Jacob, Lee, S. Hong, Wray, Naomi R., Visscher, Peter M., Mowry, Bryan J., Nertney, Deborah A., Psychosis Endophenotypes International Consortium and Wellcome Trust Case-Control Consortium 2 (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511 (7510), 421-427. doi: 10.1038/nature13595

Large-scale genomics unveils the genetic architecture of psychiatric disorders

Gratten, Jacob, Wray, Naomi R., Keller, Matthew C. and Visscher, Peter M. (2014). Large-scale genomics unveils the genetic architecture of psychiatric disorders. Nature Neuroscience, 17 (6), 782-790. doi: 10.1038/nn.3708

Life history trade-offs at a single locus maintain sexually selected genetic variation

Johnston, Susan E., Gratten, Jacob, Berenos, Camillo, Pilkington, Jill G., Clutton-Brock, Tim H., Pemberton, Josephine M. and Slate, Jon (2013). Life history trade-offs at a single locus maintain sexually selected genetic variation. Nature, 502 (7469), 93-95. doi: 10.1038/nature12489

Comparing schizophrenia symptoms in the Iban of Sarawak with other populations to elucidate clinical heterogeneity

McLean, Duncan, Barrett, Robert, Loa, Peter, Thara, Rangaswamy, John, Sujit, McGrath, John, Gratten, Jake and Mowry, Bryan (2013). Comparing schizophrenia symptoms in the Iban of Sarawak with other populations to elucidate clinical heterogeneity. Asia-Pacific Psychiatry, 7 (1), 36-44. doi: 10.1111/appy.12093

Introgression and the fate of domesticated genes in a wild mammal population

Feulner, Philine G. D., Gratten, Jacob, Kijas, James W., Visscher, Peter M., Pemberton, Josephine M. and Slate, Jon (2013). Introgression and the fate of domesticated genes in a wild mammal population. Molecular Ecology, 22 (16), 4210-4221. doi: 10.1111/mec.12378

Combined Effects of Child and Adult Elevated Blood Pressure on Subclinical Atherosclerosis: The International Childhood Cardiovascular Cohort Consortium

Juhola, Jonna, Magnussen, Costan G., Berenson, Gerald S., Venn, Alison, Burns, Trudy L., Sabin, Matthew A., Srinivasan, Sathanur R., Daniels, Stephen R., Davis, Patricia H., Chen, Wei, Kaehoenen, Mika, Taittonen, Leena, Urbina, Elaine, Viikari, Jorma S. A., Dwyer, Terence, Raitakari, Olli T. and Juonala, Markus (2013). Combined Effects of Child and Adult Elevated Blood Pressure on Subclinical Atherosclerosis: The International Childhood Cardiovascular Cohort Consortium. Circulation, 128 (3), 217-224. doi: 10.1161/CIRCULATIONAHA.113.001614

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Berndt, Sonja I., Gustafsson, Stefan, Maegi, Reedik, Ganna, Andrea, Wheeler, Eleanor, Feitosa, Mary F., Justice, Anne E., Monda, Keri L., Croteau-Chonka, Damien C., Day, Felix R., Esko, Tonu, Fall, Tove, Ferreira, Teresa, Gentilini, Davide, Jackson, Anne U., Luan, Jian'an, Randall, Joshua C., Vedantam, Sailaja, Willer, Cristen J., Winkler, Thomas W., Wood, Andrew R., Workalemahu, Tsegaselassie, Hu, Yi-Juan, Lee, Sang Hong, Liang, Liming, Lin, Dan-Yu, Min, Josine L., Neale, Benjamin M., Thorleifsson, Gudmar ... Ingelsson, Erik (2013). Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics, 45 (5), 501-U69. doi: 10.1038/ng.2606

Higher Maternal Body Mass Index Is Associated with an Increased Risk for Later Type 2 Diabetes in Offspring

Juonala, Markus, Jaaskelainen, Paula, Sabin, Matthew A., Viikari, Jorma S. A., Kahonen, Mika, Lehtimaki, Terho, Seppala, Ilkka, Hutri-Kahonen, Nina, Taittonen, Leena, Jokinen, Eero, Laitinen, Tomi, Magnussen, Costan G. and Raitakari, Olli T. (2013). Higher Maternal Body Mass Index Is Associated with an Increased Risk for Later Type 2 Diabetes in Offspring. Journal of Pediatrics, 162 (5), 918-U63. doi: 10.1016/j.jpeds.2012.10.062

Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease

Gratten, Jacob, Visscher, Peter M., Mowry, Bryan J. and Wray, Naomi R. (2013). Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease. Nature Genetics, 45 (3), 234-238. doi: 10.1038/ng.2555

Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing fetal origins of disease? The Cardiovascular Risk in Young Finns Study

Skilton, Michael R., Mikkila, Vera, Wurtz, Peter, Ala-Korpela, Mika, Sim, Kyra A., Soininen, Pasi, Kangas, Antti J., Viikari, Jorma S. A., Juonala, Markus, Laitinen, Tomi, Lehtimaki, Terho, Taittonen, Leena, Kahonen, Mika, Celermajer, David S. and Raitakari, Olli T. (2013). Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing fetal origins of disease? The Cardiovascular Risk in Young Finns Study. American Journal of Clinical Nutrition, 97 (1), 58-65. doi: 10.3945/ajcn.112.044198

Maintenance of genetic variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding

Verweij, Karin J. H., Yang, Jian, Lahti, Jari, Veijola, Juha, Hintsanen, Mirka, Pulkki-Raback, Laura, Heinonen, Kati, Pouta, Anneli, Pesonen, Anu-Katriina, Widen, Elisabeth, Taanila, Anja, Isohanni, Matti, Miettunen, Jouko, Palotie, Aarno, Penke, Lars, Service, Susan K., Heath, Andrew C., Montgomery, Grant W., Raitakari, Olli, Kahonen, Mika, Viikari, Jorma, Raikkonen, Katri, Eriksson, Johan G., Keltikangas-Jarvinen, Liisa, Lehtimaki, Terho, Martin, Nicholas G., Jarvelin, Marjo-Riitta, Visscher, Peter M., Keller, Matthew C. and Zietsch, Brendan P. (2012). Maintenance of genetic variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding. Evolution, 66 (10), 3238-3251. doi: 10.1111/j.1558-5646.2012.01679.x

Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA

Ramasamy, Adaikalavan, Kuokkanen, Mikko, Vedantam, Sailaja, Gajdos, Zofia K., Alves, Alexessander Couto, Lyon, Helen N., Ferreira, Manuel A. R., Strachan, David P., Zhao, Jing Hua, Abramson, Michael J., Brown, Matthew A., Coin, Lachlan, Dharmage, Shyamali C., Duffy, David L., Haahtela, Tari, Heath, Andrew C., Janson, Christer, Kahonen, Mika, Khaw, Kay-Tee, Laitinen, Jaana, Le Souef, Peter, Lehtimaki, Terho, Madden, Pamela A. F., Marks, Guy B., Martin, Nicholas G., Matheson, Melanie C., Palmer, Cameron D., Palotie, Aarno, Pouta, Anneli ... Hirschhorn, Joel N. (2012). Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA. PLoS One, 7 (9 Article No. e44008) e44008, e44008-1-e44008-10. doi: 10.1371/journal.pone.0044008

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

Verhoeven, Virginie J. M., Hysi, Pirro G., Saw, Seang-Mei, Vitart, Veronique, Mirshahi, Alireza, Guggenheim, Jeremy A., Cotch, Mary Frances, Yamashiro, Kenji, Baird, Paul N., Mackey, David A., Wojciechowski, Robert, Ikram, M. Kamran, Hewitt, Alex W., Duggal, Priya, Janmahasatian, Sarayut, Khor, Chiea-Chuen, Fan, Qiao, Zhou, Xin, Young, Terri L., Tai, E-Shyong, Goh, Liang-Kee, Li, Yi-Ju, Aung, Tin, Vithana, Eranga, Teo, Yik-Ying, Tay, Wanting, Sim, Xueling, Rudan, Igor, Hayward, Caroline ... Klaver, Caroline C. W. (2012). Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Human Genetics, 131 (9), 1467-1480. doi: 10.1007/s00439-012-1176-0

Childhood Physical, Environmental, and Genetic Predictors of Adult Hypertension The Cardiovascular Risk in Young Finns Study

Juhola, Jonna, Oikonen, Mervi, Magnussen, Costan G., Mikkila, Vera, Siitonen, Niina, Jokinen, Eero, Laitinen, Tomi, Wurtz, Peter, Gidding, Samuel S., Taittonen, Leena, Seppala, Ilkka, Jula, Antti, Kahonen, Mika, Hutri-Kahonen, Nina, Lehtimaki, Terho, Viikari, Jorma S. A., Juonala, Markus and Raitakari, Olli T. (2012). Childhood Physical, Environmental, and Genetic Predictors of Adult Hypertension The Cardiovascular Risk in Young Finns Study. Circulation, 126 (4), 402-409. doi: 10.1161/CIRCULATIONAHA.111.085977

Evidence of inbreeding depression on human height

McQuillan, Ruth, Eklund, Niina, Pirastu, Nicola, Kuningas, Maris, McEvoy, Brian P., Esko, Tonu, Corre, Tanguy, Davies, Gail, Kaakinen, Marika, Lyytikainen, Leo-Pekka, Kristiansson, Kati, Havulinna, Aki S., Gogele, Martin, Vitart, Veronique, Tenesa, Albert, Aulchenko, Yurii, Hayward, Caroline, Johansson, Asa, Boban, Mladen, Ulivi, Sheila, Robino, Antonietta, Boraska, Vesna, Igl, Wilmar, Wild, Sarah H., Zgaga, Lina, Amin, Najaf, Theodoratou, Evropi, Polasek, Ozren, Girotto, Giorgia ... Wilson, James F. (2012). Evidence of inbreeding depression on human height. Plos Genetics, 8 (7) e1002655, e1002655. doi: 10.1371/journal.pgen.1002655

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

Zheng, Hou-Feng, Tobias, Jon H., Duncan, Emma, Evans, David M., Eriksson, Joel, Paternoster, Lavinia, Yerges-Armstrong, Laura M., Lehtimaki, Terho, Bergstrom, Ulrica, Kahonen, Mika, Leo, Paul J., Raitakari, Olli, Laaksonen, Marika, Nicholson, Geoffrey C., Viikari, Jorma, Ladouceur, Martin, Lyytikainen, Leo-Pekka, Medina-Gomez, Carolina, Rivadeneira, Fernando, Prince, Richard L., Sievanen, Harri, Leslie, William D., Mellstrom, Dan, Eisman, John A., Moverare-Skrtic, Sofia, Goltzman, David, Hanley, David A., Jones, Graeme, Pourcain, Beate St. ... Lorentzon, Mattias (2012). WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. Plos Genetics, 8 (7) e1002745, e1002745.1-e1002745.13. doi: 10.1371/journal.pgen.1002745

Selection and microevolution of coat pattern are cryptic in a wild population of sheep

Gratten, J., Pilkington, J. G., Brown, E. A., Clutton-Brock, T. H., Pemberton, J. M. and Slate, J. (2012). Selection and microevolution of coat pattern are cryptic in a wild population of sheep. Molecular Ecology, 21 (12), 2977-2990. doi: 10.1111/j.1365-294X.2012.05536.x

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Duncan, Emma L., Ntzani, Evangelia E., Oei, Ling, Albagha, Omar M. E., Amin, Najaf, Kemp, John P., Koller, Daniel L., Li, Guo, Liu, Ching-Ti, Minster, Ryan L., Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Yerges-Armstrong, Laura M., Zheng, Hou-Feng, Alonso, Nerea, Eriksson, Joel, Kammerer, Candace M., Kaptoge, Stephen K., Leo, Paul J., Thorleifsson, Gudmar, Wilson, Scott G., Wilson, James F., Aalto, Ville ... Rivadeneira, Fernando (2012). Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics, 44 (5), 491-501. doi: 10.1038/ng.2249

The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants

Mowry, B. J. and Gratten, J. (2012). The emerging spectrum of allelic variation in schizophrenia: current evidence and strategies for the identification and functional characterization of common and rare variants. Molecular Psychiatry, 18 (1), 38-52. doi: 10.1038/mp.2012.34

Parental Smoking in Childhood and Brachial Artery Flow-Mediated Dilatation in Young Adults The Cardiovascular Risk in Young Finns Study and the Childhood Determinants of Adult Health Study

Juonala, Markus, Magnussen, Costan G., Venn, Alison, Gall, Seana, Kahonen, Mika, Laitinen, Tomi, Taittonen, Leena, Lehtimaki, Terho, Jokinen, Eero, Sun, Cong, Viikari, Jorma S. A., Dwyer, Terence and Raitakari, Olli T. (2012). Parental Smoking in Childhood and Brachial Artery Flow-Mediated Dilatation in Young Adults The Cardiovascular Risk in Young Finns Study and the Childhood Determinants of Adult Health Study. Arteriosclerosis Thrombosis and Vascular Biology, 32 (4), 1024-1031. doi: 10.1161/ATVBAHA.111.243261

Fetal Growth and Preterm Birth Influence Cardiovascular Risk Factors and Arterial Health in Young Adults The Cardiovascular Risk in Young Finns Study

Skilton, Michael R., Viikari, Jorma S. A., Juonala, Markus, Laitinen, Tomi, Lehtimaki, Terho, Taittonen, Leena, Kahonen, Mika, Celermajer, David S. and Raitakari, Olli T. (2011). Fetal Growth and Preterm Birth Influence Cardiovascular Risk Factors and Arterial Health in Young Adults The Cardiovascular Risk in Young Finns Study. Arteriosclerosis Thrombosis and Vascular Biology, 31 (12), 2975-2981. doi: 10.1161/ATVBAHA.111.234757

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

Surakka, Ida, Isaacs, Aaron, Karssen, Lennart C., Laurila, Pirkka-Pekka P., Middelberg, Rita P. S., Tikkanen, Emmi, Ried, Janina S., Lamina, Claudia, Mangino, Massimo, Igl, Wilmar, Hottenga, Jouke-Jan, Lagou, Vasiliki, van der Harst, Pim, Leach, Irene Mateo, Esko, Tonu, Kutalik, Zoltan, Wainwright, Nicholas W., Struchalin, Maksim V., Sarin, Antti-Pekka, Kangas, Antti J., Viikari, Jorma S., Perola, Markus, Rantanen, Taina, Petersen, Ann-Kristin, Soininen, Pasi, Johansson, Asa, Soranzo, Nicole, Heath, Andrew C., Papamarkou, Theodore ... Ripatti, Samuli (2011). A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genetics, 7 (10) e1002333, e1002333. doi: 10.1371/journal.pgen.1002333

Characterisation of the transcriptome of a wild great tit Parus major population by next generation sequencing

Santure, Anna W., Gratten, Jake, Mossman, Jim A., Sheldon, Ben C. and Slate, Jon (2011). Characterisation of the transcriptome of a wild great tit Parus major population by next generation sequencing. BMC Genomics, 12 (15) 283, 283.1-283.18. doi: 10.1186/1471-2164-12-283

The <i>APOE</i> -219G/T and +113G/C polymorphisms affect insulin resistance among Turks

Komurcu-Bayrak, Evrim, Onat, Altan, Yuzbasiogullari, Berna, Mononen, Nina, Laaksonen, Reijo, Kahonen, Mika, Hergenc, Gulay, Lehtimaki, Terho and Erginel-Unaltuna, Nihan (2011). The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks. Metabolism-Clinical and Experimental, 60 (5), 655-663. doi: 10.1016/j.metabol.2010.06.016

Influence of Age on Associations Between Childhood Risk Factors and Carotid Intima-Media Thickness in Adulthood The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium

Juonala, Markus, Magnussen, Costan G., Venn, Alison, Dwyer, Terence, Burns, Trudy L., Davis, Patricia H., Chen, Wei, Srinivasan, Sathanur R., Daniels, Stephen R., Kahonen, Mika, Laitinen, Tomi, Taittonen, Leena, Berenson, Gerald S., Viikari, Jorma S. A. and Raitakari, Olli T. (2010). Influence of Age on Associations Between Childhood Risk Factors and Carotid Intima-Media Thickness in Adulthood The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium. Circulation, 122 (24), 2514-2520. doi: 10.1161/CIRCULATIONAHA.110.966465

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Heid, Iris M., Jackson, Anne U., Randall, Joshua C., Winkler, Thomas W., Qi, Lu, Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Zillikens, M. Carola, Speliotes, Elizabeth K., Maegi, Reedik, Workalemahu, Tsegaselassie, White, Charles C., Bouatia-Naji, Nabila, Harris, Tamara B., Berndt, Sonja I., Ingelsson, Erik, Willer, Cristen J., Weedon, Michael N., Luan, Jianan, Vedantam, Sailaja, Esko, Tonu, Kilpelaeinen, Tuomas O., Kutalik, Zoltan, Li, Shengxu, Monda, Keri L., Dixon, Anna L., Holmes, Christopher C., Kaplan, Lee M., Liang, Liming ... Lindgren, Cecilia M. (2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics, 42 (11), 949-962. doi: 10.1038/ng.685

No evidence for warming climate theory of coat colour change in Soay sheep: A comment on Maloney et al.

Gratten, J., Wilson, A. J., McRae, A. F., Beraldi, D., Visscher, P. M., Pemberton, J. M. and Slate, J. (2010). No evidence for warming climate theory of coat colour change in Soay sheep: A comment on Maloney et al.. Biology Letters, 6 (5), 678-679. doi: 10.1098/rsbl.2010.0160

Mapping quantitative trait loci in a wild population using linkage and linkage disequilibrium analyses

Hernandez-Sanchez, J., Chatzipli, A., Beraldi, D., Gratten, J., Pilkington, J. G. and Pemberton, J. M. (2010). Mapping quantitative trait loci in a wild population using linkage and linkage disequilibrium analyses. Genetics Research, 92 (4), 273-281. doi: 10.1017/S0016672310000340

Childbearing, Child-Rearing, Cardiovascular Risk Factors, and Progression of Carotid Intima-Media Thickness The Cardiovascular Risk in Young Finns Study

Skilton, Michael R., Bonnet, Fabrice, Begg, Lisa M., Juonala, Markus, Kahonen, Mika, Lehtimaki, Terho, Viikari, Jorma S. A. and Raitakari, Olli T. (2010). Childbearing, Child-Rearing, Cardiovascular Risk Factors, and Progression of Carotid Intima-Media Thickness The Cardiovascular Risk in Young Finns Study. Stroke, 41 (7), 1332-1337. doi: 10.1161/STROKEAHA.110.579219

Genome mapping in intensively studied wild vertebrate populations

Slate, Jon, Santure, Anna W., Feulner, Philine G. D., Brown, Emily A., Ball, Alex D., Johnston, Susan E. and Gratten, Jake (2010). Genome mapping in intensively studied wild vertebrate populations. Trends in Genetics, 26 (6), 275-284. doi: 10.1016/j.tig.2010.03.005

Erratum to: Gene mapping in the wild with SNPs: Guidelines and future directions (Genetica, (2009), 136, (97-107), 10.1007/s10709-008-9317-z)

Slate, Jon, Gratten, Jake, Beraldi, Dario, Stapley, Jessica, Hale, Matt and Pemberton, Josephine M. (2010). Erratum to: Gene mapping in the wild with SNPs: Guidelines and future directions (Genetica, (2009), 136, (97-107), 10.1007/s10709-008-9317-z). Genetica, 138 (4), 467-467. doi: 10.1007/s10709-010-9445-0

The genetic basis of recessive self colour pattern in a wild sheep population

Gratten, J., Pilkington, J. G., Brown, E. A., Beraldi, D., Pemberton, J. M. and Slate, J. (2010). The genetic basis of recessive self colour pattern in a wild sheep population. Heredity, 104 (2), 206-214. doi: 10.1038/hdy.2009.105

Association genetics, population genomics, and conservation: Revealing the genes underlying adaptation in natural populations of plants and animals

Nichols, Krista M., Neale, David B., Gratten, Jake, Wilson, Alastair J., McRae, Allan F., Beraldi, Dario, Visscher, Peter M., Pemberton, Josephine M. and Slate, Jon (2010). Association genetics, population genomics, and conservation: Revealing the genes underlying adaptation in natural populations of plants and animals. Molecular Approaches in Natural Resource Conservation and Management, 123-168.

Gene mapping in the wild with SNPs: Guidelines and future directions

Slate, Jon, Gratten, Jake, Beraldi, Dario, Stapley, Jessica, Hale, Matt and Pemberton, Josephine M. (2009). Gene mapping in the wild with SNPs: Guidelines and future directions. Genetica, 136 (1), 97-107. doi: 10.1007/s10709-008-9317-z

Multiplex SNP-SCALE: A cost-effective medium-throughput SNP genotyping method

Kenta, T., Gratten, J., Haigh, N. S., Hinten, G. N., Slate, J., Butlin, R. K. and Burke, T. (2008). Multiplex SNP-SCALE: A cost-effective medium-throughput SNP genotyping method. Molecular Ecology Resources, 8 (6), 1230-1238. doi: 10.1111/j.1755-0998.2008.02190.x

A localized negative genetic correlation constrains microevolution of coat color in wild sheep

Gratten, J., Wilson, A. J., McRae, A. F., Beraldi, D., Visscher, P. M., Pemberton, J. M. and Slate, J. (2008). A localized negative genetic correlation constrains microevolution of coat color in wild sheep. Science, 319 (5861), 318-320. doi: 10.1126/science.1151182

Molecular assessment of the genetic integrity, distinctiveness and phylogeographic context of the Saltwater crocodile (Crocodylus porosus) on Palau

Russello, M. A., Brazaitis, P., Gratten, J., Watkins-Colwell, G. J. and Caccone, A. (2007). Molecular assessment of the genetic integrity, distinctiveness and phylogeographic context of the Saltwater crocodile (Crocodylus porosus) on Palau. Conservation Genetics, 8 (4), 777-787. doi: 10.1007/s10592-006-9225-7

Mapping quantitative trait loci underlying fitness-related traits in a free-living sheep population

Beraldi, Dario, McRae, Allan F., Gratten, Jacob, Slate, Jon, Visscher, Peter M. and Pemberton, Josephine M. (2007). Mapping quantitative trait loci underlying fitness-related traits in a free-living sheep population. Evolution, 61 (6), 1403-1416. doi: 10.1111/j.1558-5646.2007.00106.x

SNP-SCALE: SNP scoring by colour and length exclusion

Hinten, G. N., Hale, M. C., Gratten, J., Mossman, J. A., Lowder, B. V., Mann, M. K. and Slate, J. (2007). SNP-SCALE: SNP scoring by colour and length exclusion. Molecular Ecology Notes, 7 (3), 377-388. doi: 10.1111/j.1471-8286.2006.01648.x

Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep

Gratten, J., Beraldi, D., Lowder, B. V., McRae, A. F., Visscher, P. M., Pemberton, J. M. and Slate, J. (2007). Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep. Proceedings of the Royal Society of London: Biological Sciences, 274 (1610), 619-626. doi: 10.1098/rspb.2006.3762

Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries)

Beraldi, Dario, McRae, Allan F., Gratten, Jacob, Slate, Jon, Visscher, Peter M., Pemberton, Josephine M. and Pilkington, Jill G. (2007). Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries). Journal of Parasitology, 37 (1), 121-129. doi: 10.1016/j.ijpara.2006.09.007

Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries)

Beraldi, Dario, McRae, Allan F., Gratten, Jacob, Slate, Jon, Visscher, Peter M. and Pemberton, Josephine M. (2006). Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries). Genetics, 173 (3), 1521-1537. doi: 10.1534/genetics.106.057141

Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers

Gratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167

Connecting comorbidities with brain-gut-microbiome stress axis biology in autism spectrum disorder

Yap, Chloe, Wray, Naomi, Brix, Susanne and Gratten, Jacob (2019). Connecting comorbidities with brain-gut-microbiome stress axis biology in autism spectrum disorder. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, California, 26-31 October 2019 . Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.08.215

First genome-wide association study of schizophrenia in an Indian population reveals a novel susceptibility locus

Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Holliday, Elizabeth, Bakshi, Andrew, Jorde, Lynn, Brown, Matthew, Wray, Naomi, Suetani, Rachel, Giacomotto, Jean, Thara, Rangaswamy and Mowry, Bryan (2019). First genome-wide association study of schizophrenia in an Indian population reveals a novel susceptibility locus. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2018.08.017

Evidence for genetic overlap between schizophrenia and maternal age at first birth

Mehta, Divya, Tropf, Felix, Gratten, Jacob, Bacanu, Silviu, Bakshi, Andrew, Mowry, Bryan, Kendler, Kenneth, Yang, Jian, Visscher, Peter, McGrath, John, Mills, Melinda, Wray, Naomi and Lee, Sang Hong (2017). Evidence for genetic overlap between schizophrenia and maternal age at first birth. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, ON, Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2015.09.010

Genome-wide association study of schizophrenia in the Iban of Sarawak reveals genetic overlap with Han Chinese and, to a lesser extent, Europeans

Periyasamy, Sathish, Barrett, Robert, Yue, Weihua, Gratten, Jacob, Nertney, Deborah, McLean, Duncan, Smith, Heather, Filippich, Cheryl, Loa, Peter, Zhang, Dai, Yolken, Robert and Mowry, Bryan (2017). Genome-wide association study of schizophrenia in the Iban of Sarawak reveals genetic overlap with Han Chinese and, to a lesser extent, Europeans. 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto Canada, 16-20 October 2015. Amsterdam, Netherlands: Elsevier .

Identification of purebred Crocodylus siamensis for reintroduction in Vietnam

Fitzsimmons, Nancy Nelson, Buchan, Jason Craig, Lam, Phan Viet, Polet, Gert, Hung, Ton That, Thang, Nguyen Quoc and Gratten, Jacob (2002). Identification of purebred Crocodylus siamensis for reintroduction in Vietnam. New York: Wiley-Liss New York. doi: 10.1002/jez.10201

Microsatellite markers for Crocodylus: new genetic tools for population genetics, mating system studies and forensics

Fitzsimmons, N., Tanksley, S., Forstner, M. R. J., Louis, E. E., Daglish, R., Gratten, J. and Davis, S. (2001). Microsatellite markers for Crocodylus: new genetic tools for population genetics, mating system studies and forensics. Crocodilian Biology and Evolution, The University of Queensland, Brisbane, July 1998. Chipping Norton, NSW, Australia: Surrey Beatty & Sons.

Microsatellite markers for Crocodylus: new genetic tools for population genetics, mating system studies and forensics

Fitzsimmons, NN, Tanksley, S, Forstner, MRJ, Louis, EE, Daglish, R, Gratten, J and Davis, S (2001). Microsatellite markers for Crocodylus: new genetic tools for population genetics, mating system studies and forensics. Conference on Crocodilian Biology and Evolution, St Lucia Australia, Jul, 1998. CHIPPING NORTON NSW: SURREY BEATTY & SONS.

TRS-BIOME

Eyles, Darryl, Vasileva, Svetlina, Siskind, Dan, Alexander, Suzy, Gratten, Jake, Ko, Pauline and Vasileva, Svetlina (2024). TRS-BIOME. The University of Queensland. (Dataset) doi: 10.48610/23fd2eb

The molecular systematics, phylogeography and population genetics of Indo-Pacific Crocodylus

Gratten, Jacob (2003). The molecular systematics, phylogeography and population genetics of Indo-Pacific Crocodylus. PhD Thesis, School of Biological Sciences, The University of Queensland. doi: 10.14264/106777