The University of Queensland

Precision-guided treatment in high-risk pediatric cancers

Lau, Loretta M. S., Khuong-Quang, Dong-Anh, Mayoh, Chelsea, Wong, Marie, Barahona, Paulette, Ajuyah, Pamela, Senapati, Akanksha, Nagabushan, Sumanth, Sherstyuk, Alexandra, Altekoester, Ann-Kristin, Fuentes-Bolanos, Noemi A., Yeung, Veronica, Sullivan, Ashleigh, Omer, Natacha, Diamond, Yonatan, Jessop, Sophie, Battaglia, Lauren, Zhukova, Nataliya, Cui, Louise, Lin, Angela, Gifford, Andrew J., Fleuren, Emmy D. G., Dalla-Pozza, Luciano, Moore, Andrew S., Khaw, Seong-Lin, Eisenstat, David D., Gottardo, Nicholas G., Wood, Paul J., Tapp, Heather ... Ziegler, David S. (2024). Precision-guided treatment in high-risk pediatric cancers. Nature Medicine. doi: 10.1038/s41591-024-03044-0

TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer

Wong, Joshua K.M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. eBioMedicine, 104 105176, 105176. doi: 10.1016/j.ebiom.2024.105176

High-dose chemotherapy for Ewing sarcoma and Rhabdomyosarcoma: A systematic review by the Australia and New Zealand sarcoma association clinical practice guidelines working party

Ramamurthy, Ashika, Connolly, Elizabeth A, Mar, Jasmine, Lewin, Jeremy, Bhadri, Vivek A, Phillips, Marianne B, Winstanley, Mark, Orme, Lisa M, Grimison, Peter, Connor, Joanna, Lazarakis, Smaro, Hong, Angela M, Omer, Natacha and Cayrol, Julie (2024). High-dose chemotherapy for Ewing sarcoma and Rhabdomyosarcoma: A systematic review by the Australia and New Zealand sarcoma association clinical practice guidelines working party. Cancer Treatment Reviews, 124 102694, 102694. doi: 10.1016/j.ctrv.2024.102694

A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

Mayoh, Chelsea, Gifford, Andrew J., Terry, Rachael, Lau, Loretta M S, Wong, Marie, Rao, Padmashree, Shai-Hee, Tyler, Saletta, Federica, Khuong-Quang, Dong-Anh, Qin, Vicky, Mateos, Marion K., Meyran, Deborah, Miller, Katherine E., Yuksel, Aysen, Mould, Emily V A, Bowen-James, Rachel, Govender, Dinisha, Senapati, Akanksha, Zhukova, Nataliya, Omer, Natacha, Dholaria, Hetal, Alvaro, Frank, Tapp, Heather, Diamond, Yonatan, Pozza, Luciano Dalla, Moore, Andrew S., Nicholls, Wayne, Gottardo, Nicholas G., McCowage, Geoffrey ... Ekert, Paul G. (2023). A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer. Genome Medicine, 15 (1) 20, 20. doi: 10.1186/s13073-023-01170-x

Enhancing the potential of immunotherapy in paediatric sarcomas: breaking the immunosuppressive barrier with receptor tyrosine kinase inhibitors

Fleuren, Emmy D. G., Terry, Rachael L., Meyran, Deborah, Omer, Natacha, Trapani, Joseph A., Haber, Michelle, Neeson, Paul J. and Ekert, Paul G. (2021). Enhancing the potential of immunotherapy in paediatric sarcomas: breaking the immunosuppressive barrier with receptor tyrosine kinase inhibitors. Biomedicines, 9 (12) 1798, 1798. doi: 10.3390/biomedicines9121798

Enhancing natural killer cell targeting of pediatric sarcoma

Omer, Natacha, Nicholls, Wayne, Ruegg, Bronte, Souza-Fonseca-Guimaraes, Fernando and Rossi, Gustavo Rodrigues (2021). Enhancing natural killer cell targeting of pediatric sarcoma. Frontiers in Immunology, 12 791206, 791206. doi: 10.3389/fimmu.2021.791206

Chimeric antigen receptor T cell therapy and the immunosuppressive tumor microenvironment in pediatric sarcoma

Terry, Rachael L., Meyran, Deborah, Fleuren, Emmy D. G., Mayoh, Chelsea, Zhu, Joe, Omer, Natacha, Ziegler, David S., Haber, Michelle, Darcy, Phillip K., Trapani, Joseph A., Neeson, Paul J. and Ekert, Paul G. (2021). Chimeric antigen receptor T cell therapy and the immunosuppressive tumor microenvironment in pediatric sarcoma. Cancers, 13 (18) 4704. doi: 10.3390/cancers13184704

Phase-II trials in osteosarcoma recurrences: a systematic review of past experience

Omer, Natacha, Le Deley, Marie-Cecile, Piperno-Neumann, Sophie, Marec-Berard, Perrine, Italiano, Antoine, Corradini, Nadege, Bellera, Carine, Brugieres, Laurence and Gaspar, Nathalie (2017). Phase-II trials in osteosarcoma recurrences: a systematic review of past experience. European Journal of Cancer, 75, 98-108. doi: 10.1016/j.ejca.2017.01.005

Precision medicine search for paediatric oncology

Koopman, Bevan, Wright, Tracey, Omer, Natacha, McCabe, Veronica and Zuccon, Guido (2021). Precision medicine search for paediatric oncology. 44th International ACM SIGIR Conference on Research and Development in Information Retrieval, Virtual, 11 - 15 July, 2021. New York, NY, United States: Association for Computing Machinery. doi: 10.1145/3404835.3462792

Precision medicine for paediatric high-grade diffuse midline gliomas - results from the zero childhood cancer comprehensive precision medicine program

Khuong-Quang, Dong-Anh, Nagabushan, Sumanth, Manoharan, Neevika, Arndt, Greg, Barahona, Paulette, Cowley, Mark J, Ekert, Paul G, Failes, Tim, Bolanos, Noemi Fuentes, Gauthier, Maely, Gifford, Andrew J, Haber, Michelle, Kumar, Amit, Lock, Richard B, Marshall, Glenn M, Mayoh, Chelsea, Mould, Emily, Norris, Murray D, Gopalakrishnan, Anjana, Omer, Natacha, Trebilcock, Peter, Trahair, Toby N, Tsoli, Maria, Tucker, Katherine, Wong, Marie, Tyrrell, Vanessa, Lau, Loretta and S, Ziegler, David (2020). Precision medicine for paediatric high-grade diffuse midline gliomas - results from the zero childhood cancer comprehensive precision medicine program. 19th International Symposium on Pediatric Neuro-Oncology (ISPNO 2020), Karuizawa, Japan, 13-16 December 2020. Cary, NC, United States: Oxford University Press . doi: 10.1093/neuonc/noaa222.117